Photometric determination of coagulation time in undiluted whole blood
First Claim
1. A device for the photometric determination of coagulation in a sample of undiluted whole blood, comprising:
- (a) a container for receiving the sample of undiluted whole blood;
(b) a light emission source for emitting light, such that said light is projected onto said container; and
(c) a light detector for measuring an amount of light from said container, such that said amount of light is affected by a coagulation state of the undiluted whole blood, wherein the coagulation is determined according to said amount of light.
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Abstract
A device, system and method for photometric detection of coagulation in whole blood. The present invention is easy to implement and operate. Furthermore, the present invention has the advantage of being considered to fulfill the desired standard of using photometry for measuring blood coagulation. Also, a photometric coagulation test device for whole blood specimens according to the present invention provides medical accuracy to the home user and, at the same time, is simple to construct. The present invention is also useful for detecting and determining blood agglutination, for example as the results of a serological reaction with an antibody.
49 Citations
47 Claims
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1. A device for the photometric determination of coagulation in a sample of undiluted whole blood, comprising:
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(a) a container for receiving the sample of undiluted whole blood;
(b) a light emission source for emitting light, such that said light is projected onto said container; and
(c) a light detector for measuring an amount of light from said container, such that said amount of light is affected by a coagulation state of the undiluted whole blood, wherein the coagulation is determined according to said amount of light. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 41, 46, 47)
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38. A method for photometrically measuring coagulation in a sample of undiluted whole blood, comprising:
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providing a device for measuring coagulation of the sample, wherein said device comprises a test strip having a reaction chamber for receiving the sample for said measuring, wherein a light path with regard to the sample in said reaction chamber is less than about 10 mm;
performing at least one of transmitting light through and reflecting light from the sample; and
measuring at least one of coagulation rate and coagulation time of the sample according to at least one of transmitted or reflected light. - View Dependent Claims (39, 40)
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42-44. -44. (canceled)
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45. A method for the determination of coagulation time of a blood sample, comprising determining the coagulation time of a blood sample within a time interval shorter than the coagulation time of said sample.
Specification