Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same
First Claim
Patent Images
1. A composition comprising a polymer represented by a formula:
1 Assignment
0 Petitions
Accused Products
Abstract
Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol and a polycarboxylic acid.
112 Citations
69 Claims
- 1. A composition comprising a polymer represented by a formula:
- 30. A medical article comprising a product of a reaction consisting of at least one polyol, at least one polycarboxylic acid, and optionally an agent.
- 34. A stent comprising a coating, wherein the coating comprises a polymer represented by a formula:
-
46. A method comprising fabricating a medical article or coating, wherein the medical article or coating comprises an implantable substrate, and the method further comprises:
-
(a) preparing a polymer represented by a formula;
where R1 and R3 are optional and each comprise a component independently selected from a group consisting of substituted, unsubstituted, hetero-, straight-chained, branched, cyclic, saturated and unsaturated aliphatic radicals; and
substituted, unsubstituted, and hetero-aromatic radicals;
R2 and R4 each comprise a component independently selected from a group consisting of substituted, unsubstituted, hetero-, straight-chained, branched, cyclic, saturated and unsaturated aliphatic radicals; and
substituted, unsubstituted, and hetero-aromatic radicals; and
L1 is an optional linkage;
X is an optional agent;
L2 is an optional linkage connecting X to the polymer; and
m and n are integers not equal to 0;
(b) forming the medical article or coating, wherein the medical article or coating comprises the polymer, and the coating is formed on at least a portion of an implantable substrate; and
(c) optionally annealing the medical article or coating. - View Dependent Claims (47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57)
-
Specification