Method and apparatus for signal assessment including event rejection
First Claim
1. A method of assessing cardiac output within a living subject, comprising:
- disposing a plurality of electrodes relative to the thoracic cavity of said subject;
passing an electrical current through at least a portion of said thoracic cavity;
measuring at least one impedance waveform associated with said thoracic cavity using said current and at least one of said plurality of electrodes;
measuring at least electrocardiographic waveform having a plurality of events associated therewith;
selectively rejecting at least one of said events; and
determining cardiac output based at least in part on said impedance waveform and at least a portion of the non-rejected ones of said events.
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Accused Products
Abstract
An improved method and apparatus for non-invasively assessing one or more physiologic parameters, such as for example those associated with the circulatory system of a living organism. In one exemplary embodiment, the invention evaluates cardiac events (e.g., beats) present within an ECG waveform to determine which beats should be retained and which rejected. This evaluation is conducted based on a hierarchical method, wherein the ECG noise and morphology, as well as various aspects of the Delta Z (change in thoracic impedance), are utilized to evaluate beats for retention/rejection. In one variant, fuzzy models are used in conducting the foregoing evaluations. Parameter median filtering is also optionally applied. The foregoing techniques increase the accuracy, stability and robustness of any systems (e.g., impedance cardiographic or otherwise) which make use of the events. Improved impedance cardiographic apparatus and methods of treatment are also disclosed.
146 Citations
52 Claims
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1. A method of assessing cardiac output within a living subject, comprising:
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disposing a plurality of electrodes relative to the thoracic cavity of said subject;
passing an electrical current through at least a portion of said thoracic cavity;
measuring at least one impedance waveform associated with said thoracic cavity using said current and at least one of said plurality of electrodes;
measuring at least electrocardiographic waveform having a plurality of events associated therewith;
selectively rejecting at least one of said events; and
determining cardiac output based at least in part on said impedance waveform and at least a portion of the non-rejected ones of said events. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14)
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11. A method of assessing a hemodynamic parameter within a living subject, comprising:
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disposing at least one electrode relative to said subject;
measuring at least one cardiographic waveform from said subject using said at least one electrode, said waveform having a plurality of beats;
processing said plurality of beats to identify first beats that should be rejected, and second beats that should not be rejected; and
assessing said hemodynamic parameter based at least in part on said second beats. - View Dependent Claims (15, 16)
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- 17. Apparatus adapted to evaluate the cardiac beats of a living subject using at least one fuzzy-based noise algorithm and at least one fuzzy-based morphology algorithm.
- 20. Impedance cardiographic apparatus adapted to evaluate physiologic waveforms obtained from a living subject using a computer program adapted to evaluate criteria comprising (i) at least one ECG rejection criterion and (ii) at least one Delta Z rejection criterion.
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29. Cardiographic apparatus adapted to evaluate the cardiac beats of a living subject using:
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an ECG rejection analysis;
a Delta Z rejection analysis; and
a median filtering analysis. - View Dependent Claims (30, 31, 32, 33)
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34. A method of evaluating the cardiac beats of a living subject, comprising:
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performing an ECG rejection analysis;
performing a Delta Z rejection analysis; and
performing a median filtering analysis. - View Dependent Claims (35, 36, 37)
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38. A method of evaluating the cardiac beats of a living subject, comprising:
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performing a beat rejection analysis on a plurality of said cardiac beats;
rejecting at least one of said beats as part of said analysis; and
determining, based at least in part on said at least one rejected beat, a status of said rejection analysis. - View Dependent Claims (39, 40, 41, 42)
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43. A method of evaluating the cardiac beats of a living subject, comprising:
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providing a plurality of sources of said cardiac beats;
performing a beat rejection analysis on a plurality of said cardiac beats derived from a first of said plurality of sources;
rejecting at least one of said beats as part of said analysis; and
determining, based at least in part on said at least one rejected beat, the suitability of said first source for providing said cardiac beats. - View Dependent Claims (44, 45, 46, 47, 48)
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49. Cardiographic apparatus having an ECG evaluation module and a plurality of input vectors associated therewith, said module evaluating the cardiac beats of a living subject represented by one or more of said vectors by the method comprising:
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providing a plurality of sources of said cardiac beats;
performing a beat rejection analysis on a plurality of said cardiac beats derived from a first of said plurality of sources;
rejecting at least one of said beats as part of said analysis; and
determining, based at least in part on said at least one rejected beat, the suitability of said first source for providing said cardiac beats.
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50. A method of evaluating substantially periodic events within a time-variant waveform, comprising:
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providing a plurality of sources of said events;
performing an event rejection analysis on a plurality of said events derived from a first of said plurality of sources;
rejecting at least one of said events as part of said analysis; and
determining, based at least in part on said at least one rejected event, the suitability of said first source for providing said events. - View Dependent Claims (51, 52)
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Specification