Single-use pneumatic safety syringe providing gas-driven needle retraction

• US 20060111671A1
• Filed: 09/02/2005
• Published: 05/25/2006
• Est. Priority Date: 09/03/2004
• Status: Active Grant

• Current Assignee: L.O.M Laboratories Inc
• Original Assignee: L.O.M Laboratories Inc
• Inventors: Klippenstein, John
• Granted Patent: US 7,811,259 B2
• Time in Patent Office: Days
• US Class Current: 604/110
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/3123 having air entrapping or venting means, e.g. purging channels in pistons
• CPC Class Codes: A61M 2005/3241 Needle retraction energy is accumulated inside of a hollow plunger rod
• CPC Class Codes: A61M 2005/3242 Needle retraction by vacuum
• CPC Class Codes: A61M 5/2046 Media being expelled from injector by gas generation, e.g. explosive charge
• CPC Class Codes: A61M 5/31505 Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
• CPC Class Codes: A61M 5/31591 Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
• CPC Class Codes: A61M 5/322 Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston devices for protecting guide needles in combination with catheters A61M25/0612
• CPC Class Codes: A61M 5/3234 Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user
• CPC Class Codes: A61M 5/3293 characterised by features of the needle hub
• CPC Class Codes: A61M 5/502 for blocking the piston
• CPC Class Codes: A61M 5/508 Means for preventing re-use by disrupting the piston seal, e.g. by puncturing

Abstract

A pneumatic retractable syringe has a plunger having an interior retraction lumen. The plunger and syringe barrel have cooperating locking elements so that the plunger is locked after use within the syringe barrel. After injection of medicament is completed, the needle is retracted into the lumen by compressed gas that is released from a gas cell within the syringe when the gas cell is ruptured just before the plunger reaches the end of its downstream path of travel.

Claims

1. A safety syringe of the type for use with a hypodermic needle in which, following use of the syringe to inject medicament from its barrel, the needle is detached from the distal end of the syringe and retracted within the barrel of the syringe, thereby preventing accidental stabbing after use, comprising

a. a plunger axially movable within the barrel and having therewithin a retraction lumen open at its distal end to receive the needle after use of the syringe;

b. a gas release cell located within the assembled syringe distally of the plunger, intact and inoperative prior to substantial completion of injection of medicament by downstream motion of the plunger;

c. gas release trigger means located within the assembled syringe between the distal end of the plunger and the gas release cell, and operable in response to downstream motion of the plunger as it approaches its downstream limit of travel to cause the gas release cell to release gas into the interior of the syringe; and

d. a needle carrier for engaging the needle in the vicinity of its proximal end and carrying the needle into the lumen during retraction of the needle, the needle carrier having a distal bearing surface against which gas under pressure may bear, and movable into the plunger lumen under gas pressure so as to retract the needle into the lumen;

wherein

e. the lumen is dimensioned to receive sufficient of the combined length of the needle and the needle carrier that, after retraction, the needle is entirely within the syringe, and the needle thereafter remains in retracted position.

2. A syringe as defined in claim 1, additionally having a plunger lock for impeding or preventing unwanted re-extension of the plunger out of the barrel after use of the syringe, the plunger lock comprising

a. a plunger lock engagement element fixed to the plunger;

and

b. a cooperating lock-mate engagement element fixed to the barrel;

wherein

c. the engagement elements are located so as to make engaging contact with one another near the downstream limit of travel of the plunger; and

d. downstream motion of the plunger past the point of engaging contact causes the locking of the plunger within the barrel at or near the downstream limit of travel of the plunger.

3. A syringe as defined in claim 2, wherein the plunger lock is structured to lock the plunger to the barrel at a point in the downstream path of travel of the plunger coincident or approximately coincident with the point at which the gas release trigger means operates to cause the gas release cell to release gas.

4. A syringe as defined in claim 3, wherein the plunger lock is structured to lock the plunger to the barrel at a point in the downstream path of travel of the plunger slightly upstream of the point at which the gas release trigger means operates to cause the gas release cell to release gas.

5. A syringe as defined in claim 3, additionally having a needle re-emergence barrier that after retraction of the needle into th lumen is located downstream of the tip of the needle and operable after the needle has been retracted into the plunger lumen to prevent or impede downstream movement of the needle out of the lumen.

6. A syringe as defined in claim 5, wherein the needle re-emergence barrier comprises needle port closure means located within the barrel between the distal end of the plunger and the proximal end of the needle aperture when the needle has been assembled into the syringe and the plunger extends proximally outward from the barrel, the needle port closure means being operable as the plunger approaches the downstream limit of its path of travel to block the proximal end of the needle aperture.

7. A syringe as defined in claim 3, additionally having a gas barrier for preventing or impeding downstream escape of gas out of the syringe from the gas release cell.

8. A syringe as defined in claim 3, wherein the gas release cell is a closed cell containing a suitable substantially non-toxic non-corrosive compressed gas.

9. A syringe as defined in claim 8, wherein the gas release cell is of overall toroidal shape, so that the opening in the torus may accommodate passage therethrough of the needle.

10. A syringe as defined in claim 8, wherein the gas release trigger means comprises a perforator for rupturing the gas release cell.

11. A syringe as defined in claim 10, wherein the needle carrier is provided with a cirumferentially disposed seal for providing a sealing contact between the needle carrier and the interior surfaces of the syringe through which the needle carrier passes.

12. A syringe as defined in claim 2, whose barrel is divided internally into a smaller downstream chamber for housing the gas release cell and gas release trigger means, and an upstream chamber for containing medicament to be injected, the said chambers being separated by a radial chamber separator wall having an axial opening therein for discharge of medicament from the upstream chamber into the needle and for receiving the needle into the plunger lumen after injection.

13. A syringe as defined in claim 12, wherein the plunger has a body and a distal end whose diameter is smaller than that of the body.

14. A syringe as defined in claim 13, wherein when nearing the downstream limit of travel of the plunger, the distal end thereof penetrates the chamber separator wall through the axial opening therein, and downstream movement of the distal end of the plunger beyond the chamber separator wall causes the gas release trigger means to operate.

15. A syringe as defined in claim 14, additionally comprising within the downstream chamber an engagement ring slidably but with friction engaging the interior circumferential wall of the downstream chamber and axially movable therein, the engagement ring being located between the gas release cell and the radial separator wall and having a central aperture through which medicament from the upstream chamber into the needle may flow and for passage of the needle into the plunger lumen after injection, the engagement ring providing a buffer against which the gas cell is constrained so as to facilitate rupture of the gas cell by the perforator.

16. A syringe as defined in claim 15, wherein distal end of the plunger engages the upstream end of the engagement ring near the downstream limit of travel of the plunger, forcing the gas release cell into rupturing contact with the perforator upon completion of downstream movement of the plunger.

17. For use with a needle having a needle header, a syringe as defined in claim 16, wherein the engagement ring engages the needle header to provide support thereto and facilitates alignment of the needle and the needle header within the downstream chamber.

18. A syringe as defined in claim 17, wherein the needle carrier includes a needle port seal for blocking escape of gas and medicament through the needle and that is mounted within the plunger for frictional but sliding engagement with the inner surface of the plunger, and wherein at least the outermost circumferential portion of the needle port seal is made of resilient material so that the needle port seal may expand in diameter to fill the full cross-section of the plunger lumen within the plunger body during the needle-retraction phase of syringe operation.

19. A syringe as defined in claim 11, whose barrel is divided internally into a smaller downstream chamber for housing the gas release cell and gas release trigger means, and an upstream chamber for containing medicament to be injected, the said chambers being separated by a radial chamber separator wall having an axial opening therein for discharge of medicament from the upstream chamber into the needle and for receiving the needle into the plunger lumen after injection.

20. A syringe as defined in claim 19, wherein the plunger has a body and a distal end whose diameter is smaller than that of the body.

21. A syringe as defined in claim 20, wherein when nearing the downstream limit of travel of the plunger, the distal end thereof penetrates the chamber separator wall through the axial opening therein, and downstream movement of the distal end of the plunger beyond the chamber separator wall causes the gas release trigger means to operate.

22. A syringe as defined in claim 21, additionally comprising within the downstream chamber an engagement ring slidably but with friction engaging the interior circumferential wall of the downstream chamber and axially movable therein, the engagement ring being located between the gas release cell and the radial separator wall and having a central aperture through which medicament from the upstream chamber into the needle may flow and for passage of the needle into the plunger lumen after injection, the engagement ring providing a buffer against which the gas cell is constrained so as to facilitate rupture of the gas cell by the perforator.

23. A syringe as defined in claim 22, wherein distal end of the plunger engages the upstream end of the engagement ring near the downstream limit of travel of the plunger, forcing the gas release cell into rupturing contact with the perforator upon completion of downstream movement of the plunger.

24. A syringe as defined in claim 23, wherein the needle carrier includes a needle port seal for blocking escape of gas and medicament through the needle and that is mounted within the plunger for frictional but sliding engagement with the inner surface of the plunger, and wherein at least the outermost circumferential portion of the needle port seal is made of resilient material so that the needle port seal may expand in diameter to fill the full cross-section of the plunger lumen within the plunger body during the needle-retraction phase of syringe operation.

25. A syringe as defined in claim 11, wherein the needle carrier includes a needle port seal for blocking escape of gas and medicament through the needle and that is mounted within the plunger for frictional but sliding engagement with the inner surface of the plunger, and wherein at least the outermost circumferential portion of the needle port seal is made of resilient material so that the needle port seal may expand in diameter to fill the full cross-section of the plunger lumen during the needle retraction phase of syringe operation.