Method of coating a folded medical device
First Claim
1. A method of forming a coating on a medical device, comprising:
- providing the medical device having a surface in a collapsed configuration with at least one fold;
determining a coating material formulation to achieve a predetermined coverage of the surface of the medical device and a predetermined thickness of the coating; and
applying the coating material to form the coating on the medical device;
wherein the coating is compositioned to transfer and adhere to a targeted tissue location.
1 Assignment
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Accused Products
Abstract
A non-polymeric or biological coating applied to a radially expandable interventional medical device in a collapsed, wrapped, or folded configuration. Properties of the coating material applied to the medical device are adjusted or varied to result in a desired combination of coverage of the surface of the medical device, drug loading, and coating thickness. The coating is sterile, and is capable of being carried by a sterile medical device to a targeted tissue location within the body following radial expansion. The therapeutic coating transfers off the medical device due in part to a biological attraction with the tissue and in part to a physical transference from the medical device to the targeted tissue location in contact with the medical device.
186 Citations
26 Claims
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1. A method of forming a coating on a medical device, comprising:
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providing the medical device having a surface in a collapsed configuration with at least one fold;
determining a coating material formulation to achieve a predetermined coverage of the surface of the medical device and a predetermined thickness of the coating; and
applying the coating material to form the coating on the medical device;
wherein the coating is compositioned to transfer and adhere to a targeted tissue location. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A radially expandable medical device with a coating formed thereon, comprising:
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a body having an interior and an exterior surface; and
a therapeutic coating applied to at least a portion of the exterior surface of the body when in a collapsed configuration with at least one fold;
wherein the coating is compositioned to transfer and adhere to a targeted tissue location. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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Specification