Sterically stabilized liposome and triamcinolone composition for treating the respiratory tract of a mammal
First Claim
1. A composition comprising a sterically stabilized liposome in combination with triamcinolone for aerosol administration, the sterically stabilized liposome being compatible with a respiratory tract of a mammal and effective to extend the effective life of the triamcinolone in the respiratory tract by a time equal to at least twice the effective life of the triamcinolone alone.
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Abstract
This invention relates to a composition containing a sterically stabilized liposome and triamcinolone, effective for the treatment of a mammal, with the composition being adapted for administration as an aerosol and with the composition providing effective treatment for a period of time at least 1.5 times as long as the effective time for treatment with triamcinolone alone. This invention also relates to a method for treating a mammal respiratory tract with the composition.
14 Citations
27 Claims
- 1. A composition comprising a sterically stabilized liposome in combination with triamcinolone for aerosol administration, the sterically stabilized liposome being compatible with a respiratory tract of a mammal and effective to extend the effective life of the triamcinolone in the respiratory tract by a time equal to at least twice the effective life of the triamcinolone alone.
- 16. A method for treating a respiratory tract of a mammal by aerosol administration of an effective amount of a composition comprising a sterically stabilized liposome in combination with triamcinolone, the sterically stabilized liposome being compatible with the respiratory tract of a mammal and effective to extend the effective life of triamcinolone in the respiratory tract by a time equal to at least twice the effective life of triamcinolone alone.
Specification