Contrast-enhancing aspheric intraocular lens

• US 20060116763A1
• Filed: 12/01/2004
• Published: 06/01/2006
• Est. Priority Date: 12/01/2004
• Status: Abandoned Application

• Current Assignee: Alcon Incorporated
• Original Assignee: Alcon Incorporated
• Inventors: Simpson, Michael J.
• Application Number:
  US11/000,728
• Publication Number:
  US 20060116763A1
• Time in Patent Office: Days
• US Class Current: 623/6.230
• CPC Class Codes: A61F 2/1613 having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
• CPC Class Codes: A61F 2/164 Aspheric lenses

Abstract

The present invention provides an intraocular lens (IOL) having an optic with a posterior and an anterior refractive surfaces, at least one of which has an aspherical profile, typically characterized by a non-zero conic constant, for controlling the aberrations of a patient'"'"'s eye in which the IOL is implanted. Preferably, the IOL'"'"'s asphericity, together with the aberrations of the patient'"'"'s eye, cooperate to provide an image contrast characterized by a calculated modulation transfer function (MTF) of at least about 0.25 and a depth of field of at least about 0.75 Diopters.

Claims

1. An intraocular lens (IOL), comprising:

an optic having an anterior refractive surface and a posterior refractive surface,

at least one of said anterior or posterior surfaces being characterized by an aspheric profile for controlling the aberrations of an eye in which the IOL is implanted such that a combined lens and cornea exhibit a peak calculated modulation transfer function (MTF) contrast of at least about 0.25 and a depth of field of at least about 0.75 diopters for pupil diameters in a range of about 4.5 mm to about 5 mm for monochromatic light at a wavelength of about 550 nm.

2. The IOL of claim 1, wherein said aberrations of the eye comprises a spherical aberration of the cornea.

3. The IOL of claim 1, wherein said combined lens and cornea exhibit a modulation transfer function (MTF) at the retina greater than about 0.3 for 50 line pairs per mm and a wavelength of about 550 nm.

4. The IOL of claim 1, wherein said combined lens and cornea exhibit a modulation transfer finction (MTF) greater than about 0.35 for 50 line pairs per mm and a wavelength of about 550 mn.

5. The IOL of claim 1, wherein said combined lens and cornea exhibit a modulation transfer finction (MTF) in a range of about 0.25 to about 0.4 at a spatial frequency of about 50 1 p/mm, a wavelength of about 550 nm and a pupil size of about 4.5 mm.

6. The IOL of claim 1, wherein said optic is formed of a biocompatible soft material.

7. The IOL of claim 6, wherein said optic is formed of a soft acrylic material and exhibits an aspherical conic constant in a range of about 0 to about −

50.

8. The IOL of claim 6, wherein said optic is formed of hydrogel and exhibits an aspherical conic constant in a range of about 0 to about −

50.

9. The IOL of claim 6, wherein said optic is formed of silicone and exhibits an aspherical conic constant in a range of about 0 to about −

50.

10. The IOL of claim 1, wherein said anterior surface is characterized by said aspheric profile exhibiting a selected deviation from a putative spherical profile having a radius of curvature R₁.

11. The IOL of claim 10, wherein said posterior surface is characterized by a spherical profile having a radius of curvature of R₂, wherein R₂ is larger than R₁.

12. The IOL of claim 11, wherein said lens exhibits a shape factor K defined as:

$X=\frac{R_2+R_1}{R_2-R_1},$

wherein K is in a range of about 0 to about +1.

13. The IOL of claim 10, wherein said posterior surface is characterized by an aspheric base profile exhibiting a selected deviation from a putative spherical profile having a radius of curvature of R₂, wherein R₂ is larger than R₁.

14. An IOL, comprising:

a refractive optic providing a nominal diopter optical power,

said optic having a surface with an aspherical profile for controlling aberrations of an eye of a patient in which said lens is implanted so as to enhance the patient'"'"'s image contrast relative to that by a substantially identical lens having a spherical optic, while providing the patient with a depth of field greater than about 0.75.

15. The IOL of claim 14, wherein said combined aspherical lens and the cornea exhibit a peak modulation transfer function (MTF) contrast of at least about 0.25 for 50 line pairs per millimeter and a substantially monochromatic wavelength of about 550 nm.

16. The IOL of claim 14, wherein said aspherical profile is adapted for controlling a spherical aberration of the cornea.

17. The IOL of claim 14, wherein said aspherical refractive surface comprises an anterior surface of said lens.

18. The IOL of claim 14, wherein said aspherical refractive surface comprises a posterior surface of said lens.

19. The IOL of claim 14, wherein said diopter optical power is in a range of about 0 to about 40.

20. An IOL, comprising

an optic having an anterior surface and a posterior surface,

at least one of said surfaces having an aspherical profile for controlling aberrations of an eye of a patient in which the lens is implanted so as to provide the patient with an image contrast characterized by a modulation transfer function (MTF) of at least about 0.25 and a depth of field of at least about 0.75 Diopters.

21. The IOL of claim 20, wherein said lens provides the patient with an MTF in a range of about 0.25 to about 0.4.

22. The IOL of claim 20, wherein said lens provides the patient with a depth of field of in a range of about 0.75 to about 1.5 diopters.

23. The IOL of claim 20, wherein said aspherical profile controls aberrations exhibited by the cornea.

24. The IOL of claim 20, wherein said aspherical profile controls aberrations exhibited by the combined cornea and the natural lens.

25. An intraocular lens, comprising:

an optic having at least one refractive surface,

said refractive surface having an aspheric portion for controlling average aberrations exhibited by the eyes of a selected patient group such that upon implantation of said lens in a patient'"'"'s eye the combined lens and the cornea exhibit a peak modulation transfer function (MTF) contrast of at least about 0.25 for monochromatic light having a wavelength of 550 nm and a depth of field of at least about 0.75 Diopters.

26. The IOL of claim 25, wherein said refractive surface comprises any of an anterior surface or a posterior surface of the said lens.

27. An intraocular lens, comprising:

an optic comprising at least one refractive surface having a base characterized by a profile described by the following relation;

$z=\frac{{\mathrm{CR}}^2}{1+\sqrt{1-\left(1+Q\right)<br><br>C^2<br><br>R^2}}+{\mathrm{AR}}^4+{\mathrm{BR}}^6,$

wherein

z denotes a sag of the surface parallel to an axis (z) perpendicular to the surface,

C denotes a curvature at the vertex of the surface,

Q denotes a conic coefficient,

R denotes a radial position on the surface,

A denotes a fourth order deformation coefficient, and

B denotes a sixth order deformation coefficient,

wherein Q is in a range of about 0 to about 100, A is in a range of about −

1×

10<sup>−

3</sup> to about 1×

10<sup>−

3</sup>, and B is in a range of about −

1×

10<sup>−

4</sup> to about 1×

10<sub>−

4</sub>.

28. A method of designing an intraocular lens having an anterior and a posterior refractive surface, comprising:

deriving a model average of aberrations of the eye based on wavefront measurements of aberrations exhibited by the eyes of a selected patient population, and

adjusting asphericity of at least one of said refractive surfaces for controlling said average aberrations such that a patient in which the lens is implanted would exhibit an image contrast characterized by a peak modulation transfer function (MTF) contrast of at least about 0.25 and a depth of field of at least about 0.75 D.

29. An intraocular lens (IOL), comprising:

an optic having an anterior refractive surface and a posterior refractive surface,

at least one of said surfaces having a generally toric shape exhibiting different optical power values along two orthogonal surface directions and having an asphericity along at least one of said orthogonal directions for controlling aberrations of an eye in which the IOL is implanted such that the combination of the lens and the eye exhibits a modulation transfer function of at least about 0.25 and a depth of field of at least about 0.75 D for a pupil size of about 4.5 mm and a monochromatic wavelength of about 550 nm as calculated in a model eye.