Electrochemical Analyte Sensor
First Claim
1. An electrochemical sensor comprising:
- a substrate;
a first conductive material disposed on a surface of the substrate to form one or more working electrodes;
one or more contact pads in electrical contact with the one or more working electrodes;
a second conductive material disposed on a surface of the substrate to form a counter electrode, a reference electrode, or a counter-reference electrode;
a contact pad in electrical contact with the counter electrode, reference electrode or counter-reference electrode;
an enzyme disposed proximate to the working electrode; and
an analyte mass transport limiting layer disposed over at least a portion of the working electrode to limit transport of an analyte to the working electrode, wherein the portion of the working element having the analyte mass transport limiting layer is configured and arranged for subcutaneous implantation into the body of an animal for contact with body fluid of the animal.
3 Assignments
0 Petitions
Accused Products
Abstract
An electrochemical analyte sensor having conductive traces on a substrate is used to determine a level of analyte in in vitro or in vivo analyte-containing fluids. The electrochemical analyte sensor includes a substrate and conductive material disposed on the substrate, the conductive material forming a working electrode. In some sensors, the conductive material is disposed in recessed channels formed in a surface of the sensor. An electron transfer agent and/or catalyst may be provided to facilitate the electrolysis of the analyte or of a second compound whose level depends on the level of the analyte. A potential is formed between the working electrode and a reference electrode or counter/reference electrode and the resulting current is a function of the concentration of the analyte in the fluid.
-
Citations
19 Claims
-
1. An electrochemical sensor comprising:
-
a substrate;
a first conductive material disposed on a surface of the substrate to form one or more working electrodes;
one or more contact pads in electrical contact with the one or more working electrodes;
a second conductive material disposed on a surface of the substrate to form a counter electrode, a reference electrode, or a counter-reference electrode;
a contact pad in electrical contact with the counter electrode, reference electrode or counter-reference electrode;
an enzyme disposed proximate to the working electrode; and
an analyte mass transport limiting layer disposed over at least a portion of the working electrode to limit transport of an analyte to the working electrode, wherein the portion of the working element having the analyte mass transport limiting layer is configured and arranged for subcutaneous implantation into the body of an animal for contact with body fluid of the animal. - View Dependent Claims (2, 3, 4, 5, 6)
-
-
7. An electrochemical sensor, comprising:
-
a substrate;
conductive material disposed on a surface of the substrate to form a plurality of traces, at least one of the traces forming a working electrode; and
an enzyme disposed proximate to the working electrode;
wherein at least two of conductive traces are separated on the surface of the substrate by 150 μ
m or less. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14)
-
-
15. An electrochemical sensor, comprising:
-
a substrate;
conductive material disposed on a surface of the substrate to form a plurality of traces, at least one of the traces forming a working electrode; and
an enzyme disposed proximate to the working electrode;
wherein the plurality of conductive traces are disposed on the surface of the substrate at a density, along a width of the substrate, of about 150 to 700 μ
m/trace or less. - View Dependent Claims (16, 17, 18, 19)
-
Specification