Systems and methods for measuring sodium concentration in saliva
First Claim
1. A measurement system comprising:
- a sample collector adapted to collect a saliva sample;
a measurement device comprising a chromatography chamber and a chromatography buffer;
a solid phase chromatography medium, said medium having a labeling system which produces a visible label in the presence of sodium, and wherein the sample collector is configured to deliver collected sample to the chromatography medium.
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Abstract
Systems and methods for measuring saliva sodium concentration using a chromatographic reaction enable rapid-results, low-cost diagnosis of various medical conditions in an outpatient setting. In one embodiment, measured patient saliva sodium concentration is used by the patient or the patient'"'"'s healthcare provider to guide medical decision making. In another embodiment, measured patient saliva sodium concentration is processed to mechanically adjust the concentration of sodium in an aqueous solution to be delivered to the patient for oral administration. In yet another embodiment, a closed loop system measures saliva sodium concentration and uses any of a number of different types of feedback control systems to monitor and control the fluid and/or electrolyte state of the patient.
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Citations
41 Claims
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1. A measurement system comprising:
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a sample collector adapted to collect a saliva sample;
a measurement device comprising a chromatography chamber and a chromatography buffer;
a solid phase chromatography medium, said medium having a labeling system which produces a visible label in the presence of sodium, and wherein the sample collector is configured to deliver collected sample to the chromatography medium. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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37. A method for determining a level of dehydration in the patient, wherein the level of dehydration is based upon measured saliva sodium concentration.
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38. A method for rehydrating a patient, said method comprising:
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determining a level of dehydration in the patient; and
preparing a rehydration fluid by combining an amount of sodium with an aqueous component, wherein the amount of sodium is selected based on the determined level of dehydration. - View Dependent Claims (39, 40)
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41. A rehydration system comprising:
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a measurement device which analyzes a patient sample to determine a level of rehydration; and
a drinking device which combines an aqueous component and an amount of an electrolyte selected based on the measured level of dehydration.
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Specification