Bone treatment systems and methods

• US 20060122614A1
• Filed: 08/02/2005
• Published: 06/08/2006
• Est. Priority Date: 12/06/2004
• Status: Abandoned Application

• Current Assignee: Dfine Incorporated (Merit Medical Systems, Inc.)
• Original Assignee: Dfine Incorporated (Merit Medical Systems, Inc.)
• Inventors: Shadduck, John H., Truckai, Csaba, Luzzi, Robert, Carlson, Grace A.
• Application Number:
  US11/196,089
• Publication Number:
  US 20060122614A1
• Time in Patent Office: Days
• US Class Current: 606/76
• CPC Class Codes: A61B 17/7095 the filler comprising unlinked macroscopic particles
• CPC Class Codes: A61B 17/7098 wherein the implant is permeable or has openings, e.g. fenestrated screw hollow surgical screws A61B17/864
• CPC Class Codes: A61B 17/864 hollow, e.g. with socket or cannulated
• CPC Class Codes: A61B 17/8811 characterised by the introducer tip, i.e. the part inserted into or onto the bone
• CPC Class Codes: A61B 17/8836 for heating, cooling or curing of bone cement or fluid fillers
• CPC Class Codes: A61B 2017/00022 Sensing or detecting at the treatment site
• CPC Class Codes: A61B 2017/00026 Conductivity or impedance, e.g. of tissue
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61F 2/44 for the spine, e.g. vertebrae, spinal discs

Abstract

The present invention relates in certain embodiments to medical devices for treating osteoplasty procedures such as vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the geometry of fill material introduced into cancellous bone. An exemplary system utilizes Rf energy in combination a conductive bone fill material for polymerizing the surface of the inflow plume to control the geometry of the fill material and the application of force caused by inflows of fill material. In another embodiment, method of treating bone includes injecting a volume of fill material into a bone and selectively modifying a viscosity of a selected portion of the bone filler to control the direction of flow of the fill material within the bone. A system for treating bone using this method includes an introducer for delivering fill material into the bone and an energy source selectively coupleable to the fill material to alter the viscosity of the fill material as it flows out of the introducer.

Claims

1. A bone fill material comprising:

an in-situ hardenable component; and

an electrically conductive filler component that enables the bone fill material to function as an electrode.

2. The bone fill material of claim 1, wherein the in-situ hardenable component includes at least one of PMMA, monocalcium phosphate, tricalcium phosphate, calcium carbonate, calcium sulphate or hydroxyapatite.

3. The bone fill material of claim 1, wherein the conductive filler component is a biocompatible metal or carbon.

4. The bone fill material of claim 3, wherein the metal includes at least one of titanium, tantalum, stainless steel, silver, gold, platinum, nickel, tin, nickel titanium alloy, palladium, magnesium, iron, molybdenum, tungsten, zirconium, zinc, cobalt or chromium and alloys thereof.

5. The bone fill material of claim 1, wherein the conductive filler component is in the form of at least one of filaments, particles, microspheres, spheres, powders, grains, flakes, granules, crystals, rods, tubules.

6. The bone fill material of claim 1, wherein the conductive filler component is at least one of solid, porous and hollow.

7. The bone fill material of claim 1, wherein the conductive filler component comprises a non-conductive core portion with a conductive cladding.

8. The bone fill material of claim 7, wherein the non-conductive core portion is selected from the group consisting of glass, ceramic and polymer materials.

9. The bone fill material of claim 1, wherein the conductive filler component has a mean dimension across a principal axis ranging from about 0.5 micron to 2000 microns.

10. A bone fill material comprising:

a composite including an in-situ hardenable component and a filler component having at least one of an energy-absorbing property and an energy-transmitting property for cooperating with a remote energy source for absorbing energy for polymerizing the composite or for transmitting energy for heating tissue adjacent the composite.

11. The bone fill material of claim 10, wherein the filler component is a conductive filler component selected from the group consisting of filaments, particles, microspheres, spheres, powders, grains, flakes, granules, crystals, rods, tubules, nanotubes, scaffolds and structures assembled thereof.

12. The bone fill material of claim 11, wherein the conductive filler is rigid.

13. The bone fill material of claim 11, wherein the conductive filler is non-rigid.

14. The bone fill material of claim 11, wherein the conductive filler is porous.

15. The bone fill material of claim 11, wherein the conductive filler includes carbon nanotubes.

16. The bone fill material of claim 10, wherein the filler component is a conductive filler component selected from at least one of titanium, tantalum, stainless steel, silver, gold, platinum, nickel, tin, nickel titanium alloy, palladium, magnesium, iron, molybdenum, tungsten, zirconium, zinc, cobalt, chromium or carbon.

17. The bone fill material of claim 10, wherein the hardenable component includes at least one of PMMA, monocalcium phosphate, tricalcium phosphate, calcium carbonate, calcium sulphate or hydroxyapatite.

18. The bone fill material of claim 10, wherein the filler component is a conductive filler component comprising a non-conductive core portion with a conductive cladding.

19. The bone fill material of claim 18, wherein the non-conductive core portion is selected from the group consisting of glass, ceramic and polymer materials.

20. The bone fill material of claim 10, wherein the filler component is a conductive filler component comprising filaments having a mean dimension across a minor axis ranging between about 1 micron and 500 microns.

21. The bone fill material of claim 20, wherein the filaments have a length ranging from about 1 mm to 10 mm.

22. A bone fill material comprising:

an in-situ hardenable cement component; and

an electrically conductive filler component comprising a biocompatible conductive metal, wherein the filler component comprises microfilaments enabling the bone fill material to function as an electrode.

23. The bone fill material of claim 22, wherein the in-situ hardenable cement component comprises PMMA.

24. The bone fill material of claim 22, wherein the biocompatible conductive metal is selected from the group consisting of titanium, tantalum, stainless steel, silver, gold, platinum, nickel, tin, nickel titanium alloy, palladium, magnesium, iron, molybdenum, tungsten, zirconium, zinc, cobalt or chromium and alloys thereof.

25. The bone fill material of claim 22, wherein the microfilaments are plated with a conductive metal.

26. The bone fill material of claim 25, wherein the microfilaments are made of titanium or stainless steel and are plated with gold or silver.

27. The bone fill material of claim 25, wherein the microfilaments are made of stainless steel and are plated with gold.

28. The bone fill material of claim 22, comprising about 0.5% to 20% microfilaments by weight.

29. The bone fill material of claim 22, comprising about 1% to 10% microfilaments by weight.

30. The bone fill material of claim 22, comprising about 2% to 5% microfilaments by weight.

31. The bone fill material of claim 22, wherein the microfilaments have a mean diameter of between about 1 and 500 microns.

32. The bone fill material of claim 22, wherein the microfilaments have a mean diameter of between about 1 and 50 microns.

33. The bone fill material of claim 22, wherein the microfilaments have a mean length of between about 1 and 10 mm.