Device and method for multiple analyte detection
First Claim
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1. A device comprising:
- a substrate;
a sample-distribution network defined by the substrate and comprising (i) a sample inlet, (ii) two or more detection chambers, and (iii) channel means providing dead-end fluid connections between the detection chambers and the inlet; and
detection reagents in the two or more detection chambers;
wherein the substrate comprises two or more layers and at least one of the two or more layers comprises a heat-conducting metal.
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Abstract
The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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Citations
20 Claims
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1. A device comprising:
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a substrate;
a sample-distribution network defined by the substrate and comprising (i) a sample inlet, (ii) two or more detection chambers, and (iii) channel means providing dead-end fluid connections between the detection chambers and the inlet; and
detection reagents in the two or more detection chambers;
wherein the substrate comprises two or more layers and at least one of the two or more layers comprises a heat-conducting metal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A device comprising:
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a substrate;
a sample-distribution network defined by the substrate and comprising (i) a sample inlet, (ii) two or more detection chambers, and (iii) channel means providing dead-end fluid connections between the detection chambers and the inlet; and
detection reagents in the detection chambers;
wherein the substrate comprises two or more layers and a high thermal conductivity metal surface. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification