Process for the production of an active molecule vector used to diffuse active substances and vector thus obtained
First Claim
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1. Process for the production of an active molecule vector that can be applied in the biomedical field, characterized in that it comprises the following stages:
- Diluting a monomer that has at least two NH2 groups that are separated by at least four carbons in water, Adjusting the pH to a value of between 6.5 and 7.5, Adding glutaraldehyde, OHC—
(CH2)3—
COH, and Awaiting the polycondensation reaction and the formation of imines, and Recovering the poly(monomer-G) that is obtained.
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Abstract
A process for the production of an active molecule vector that can be applied in the biomedical field, includes the following stages:
- Diluting a monomer that has at least two NH2 groups that are separated by at least four carbons in water, Adjusting the pH to a value of between 6.5 and 7.5,
- Adding glutaraldehyde, OHC—(CH2)3—COH, and Awaiting the polycondensation reaction and the formation of imines, and Recovering the poly(monomer-G) that is obtained. The monomer is selected from among the L-ornithine, the L-lysine or the L-citrulline. Further described are the biomedical vector that is obtained, and the use as a vector of active molecules, such as fatty acids, antioxidants, vitamin-enriched compounds or neurotransmitters for having bacteriostatic, anti-allergenic, anti-parasitic, anti-predatory or antifungal, anti-inflammatory or immunomodulating activities.
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Citations
20 Claims
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1. Process for the production of an active molecule vector that can be applied in the biomedical field, characterized in that it comprises the following stages:
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Diluting a monomer that has at least two NH2 groups that are separated by at least four carbons in water, Adjusting the pH to a value of between 6.5 and 7.5, Adding glutaraldehyde, OHC—
(CH2)3—
COH, andAwaiting the polycondensation reaction and the formation of imines, and Recovering the poly(monomer-G) that is obtained. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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10. Molecule vector that can be applied in the biomedical field, wherein the molecule comprises the poly(ornithine-G), the poly(L-lysine-G) or the poly(L-citrulline-G) to which are grafted active molecules such as fatty acids, antioxidants, vitamin-enriched compounds, hormones, medications or neurotransmitters for having bacteriostatic, anti-allergenic, anti-parasitic, anti-predatory, antifungal, anti-inflammatory or immunomodulating activities.
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11. A method of receiving at least one of fatty acids, antioxidants, vitamin-enriched compounds and neurotransmitters for having bacteriostatic, anti-allergenic, anti-parasitic, anti-predatory, antifungal, anti-inflammatory or immunomodulating activities, the method comprising applying an effective amount of a molecule vector comprising at least one of the poly(ornithine-G), the poly(L-lysine-G) and the poly(L-citrulline-G) to which are grafted active molecules selected from a group consisting of fatty acids, antioxidants, vitamin-enriched compounds, hormones, medications and neurotransmitters.
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