Systems for and methods of atrioventricular valve regurgitation and reversing ventricular remodeling
First Claim
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1. (R L, J H, L G) A method for reducing regurgitation of an atrioventricular valve of a heart, comprising the steps of:
- securing an apparatus to an exterior wall segment of a heart, said apparatus having a compression member in contact with said exterior wall segment of the heart; and
displacing said compression member, thereby moving said exterior wall segment inward and toward the center line of the ventricular cavity of the heart so as to normalize papillary muscle geometry and improve leaflet coaptation.
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Abstract
Methods of and devices for restoring the normal geometry of a heart, including but not limited to the structures supporting the atrioventricular valves. The techniques and devices described herein operate on the principle of displacement, both active and passive, to reverse cardiac remodeling and limit ischemic atrioventricular valve regurgitation.
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Citations
143 Claims
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1. (R L, J H, L G) A method for reducing regurgitation of an atrioventricular valve of a heart, comprising the steps of:
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securing an apparatus to an exterior wall segment of a heart, said apparatus having a compression member in contact with said exterior wall segment of the heart; and
displacing said compression member, thereby moving said exterior wall segment inward and toward the center line of the ventricular cavity of the heart so as to normalize papillary muscle geometry and improve leaflet coaptation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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26. (R L, J H, L G) An apparatus for reducing regurgitation of an atrioventricular valve of a heart, comprising:
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a compression member adapted to contact an exterior wall segment of a heart;
a displacement mechanism for moving said compression member inward and toward the center line of the ventricular cavity of the heart so as to normalize papillary muscle geometry and thereby improve leaflet coaptation; and
means for securing the compression member to the exterior wall of the heart. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54)
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55. (R L, J H, L G) A method for reducing regurgitation of an atrioventricular valve of a heart, comprising the steps of:
securing an apparatus to an exterior wall segment of a heart, said apparatus having an indented compression member in contact with said exterior wall segment of the heart, so as to move said exterior wall segment inward and toward the center line of the ventricular cavity of the heart so as to normalize papillary muscle geometry and improve leaflet coaptation. - View Dependent Claims (56, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68)
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69. (R L, J H, L G) An apparatus for reducing regurgitation of an atrioventricular valve of a heart, comprising:
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an indented compression member adapted to contact an exterior wall segment of a heart so as to move said exterior wall segment inward and toward the center line of the ventricular cavity of the heart so as to normalize papillary muscle geometry and improve leaflet coaptation; and
means for securing the compression member to the exterior wall of the heart. - View Dependent Claims (70, 72)
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71. (R L, J H, L G) The apparatus of clam 69, wherein the compression member has a contour related to the contour of said exterior wall segment.
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73. (R L, J H, L G) A method of reversing cardiac remodeling, comprising the steps of:
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securing an apparatus to an exterior wall segment of a heart, said apparatus including a compression member in contact with said exterior wall segment of the heart;
and actively displacing said compression member so as to cyclically move said exterior wall segment inward and toward the center line of the ventricular cavity, thereby normalizing cardiac geometry. - View Dependent Claims (74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91)
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92. (R L, J H, L G) An apparatus for reversing cardiac remodeling, comprising:
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a compression member adapted to contact an exterior wall segment of a heart;
an active displacement mechanism for cyclically moving said compression member inward and toward the center line of the ventricular cavity of the heart so as to normalize cardiac geometry; and
means for securing the compression member to the exterior wall segment of the heart. - View Dependent Claims (93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109)
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110. (R L, J H, L G) A method of reversing cardiac remodeling, comprising the steps of:
securing an apparatus to an external wall segment of a heart, said apparatus including a compression member in contact with said exterior wall segment of the heart, a buttressing portion, and a region between said compression member and said buttressing portion within which is disposed a stiffening material, such that said compression member is displaced so as to move said exterior wall segment inward and toward the center line of the ventricular cavity, thereby normalizing cardiac geometry. - View Dependent Claims (111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121)
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122. (R L, J H, L G, G V) A method of reversing cardiac remodeling, comprising the step of:
delivering a material into a region of tissue of the heart so as to displace a portion of the region of tissue inward and toward the center line of the ventricular cavity, thereby normalizing cardiac geometry - View Dependent Claims (124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143)
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123. (R L, J H, L G, G V) A method for reducing regurgitation of an atrioventricular valve of a heart, comprising the steps of:
delivering a material into a muscle wall region of a heart proximate the papillary muscle, said material displacing a portion of said muscle wall region inward and toward the center line of the ventricular cavity of the heart so as to normalize papillary muscle geometry and improve leaflet coaptation.
Specification