Use of extracellular matrix and electrical therapy
First Claim
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1. A method comprising contacting an isolated extracellular matrix (ECM) support with one or more electrodes, which one or more electrodes are optionally connected to the distal end of one or more connectors.
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Abstract
The invention provides methods and devices useful for cardiac repair.
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Citations
36 Claims
- 1. A method comprising contacting an isolated extracellular matrix (ECM) support with one or more electrodes, which one or more electrodes are optionally connected to the distal end of one or more connectors.
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17. A method, comprising:
- introducing to a mammal an implantable device comprising a sensor to sense a physiological signal indicative of a predetermined cardiac condition, one or more electrodes comprising isolated ECM, and a generator coupled to the sensor and the one or more electrodes, the generator adapted to control an electrical therapy; and
applying electrical therapy, so as to modulate remodeling in the mammal after cardiac injury based on at least the sensed physiological signal. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
- introducing to a mammal an implantable device comprising a sensor to sense a physiological signal indicative of a predetermined cardiac condition, one or more electrodes comprising isolated ECM, and a generator coupled to the sensor and the one or more electrodes, the generator adapted to control an electrical therapy; and
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28. A method comprising:
- delivering electrical therapy to cardiac tissue of a mammal using an implantable pulse generator having isolated ECM applied thereto, wherein the electrical therapy enhances the regenerative and/or repair properties of the isolated ECM.
- View Dependent Claims (29, 30, 31, 32, 33, 34, 35, 36)
Specification