Slide-and-lock stent

• US 20060136041A1
• Filed: 12/17/2004
• Published: 06/22/2006
• Est. Priority Date: 12/17/2004
• Status: Active Grant

• Current Assignee: REVA Medical Inc.
• Original Assignee: REVA Medical Inc.
• Inventors: Schmid, Eric V., Jackson, Thomas R., Nguyen, John D., Matsuura, David G., Gillespie, Walter D., Morris, Andrew, Moore, Daniel, Zeltinger, Joan, Simpson, Philip J., Eisele, Robert F., Padilla, Orlando M., Howard, Steven C., Esser, Keith Allen, DiPari, Joseph Anthony, Brandon, Donald K.
• Granted Patent: US 8,292,944 B2
• Time in Patent Office: Days
• US Class Current: 623/1.160
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/92 Stents in the form of a rolled-up sheet expanding after insertion into the vessel , e.g. with a spiral shape in cross-section
• CPC Class Codes: A61F 2/93 circumferentially expandable by using ratcheting locks
• CPC Class Codes: A61F 2210/0076 multilayered, e.g. laminated structures
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: B33Y 80/00 Products made by additive manufacturing

Abstract

The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.

Claims

1. A slide-and-lock stent, comprising a tubular member having longitudinal and circumferential axes, said tubular member comprising at least two circumferentially adjacent modules, each comprising at least two slide-and-lock radial elements which are separated from one another in the longitudinal axis, wherein each slide-and-lock radial element comprises an engaging tab and a receiving slot which comprises a lockout tooth therein and defines a travel path, wherein engaging tabs from the slide-and-lock radial elements from each module are slidably engaged within receiving slots in the slide-and-lock radial elements from a circumferentially adjacent module, wherein the lockout tooth is configured to permit one-way sliding of the tabs along the travel path, such that said tubular member achieves expansion in the circumferential axis with reduced recoil as the circumferentially adjacent modules slide apart from one another.

2. The slide-and-lock stent of claim 1, wherein the travel path is aligned substantially in the circumferential axis.

3. The slide-and-lock stent of claim 1, wherein the lockout tooth further comprises a plurality of lockout teeth which are disposed along both proximal and distal sides of the slot.

4. The slide-and-lock stent of claim 3, wherein the plurality of lockout teeth are substantially evenly distributed on the proximal and distal sides of the slot.

5. The slide-and-lock stent of claim 4, wherein the lockout teeth on the proximal side are circumferentially offset from the lockout teeth on the distal side, such that the travel path defines a zig-zag pattern.

6. The slide-and-lock stent of claim 1, further comprising at least one passive radial element disposed between the longitudinally separated slide-and-lock radial elements in each module, wherein said passive radial element further comprises a tab and a slot, and wherein tabs from said passive radial element from one module are slidably engaged within slots in said passive radial element from a circumferentially adjacent module.

7. The slide-and-lock stent of claim 6, wherein at least one slot from the passive radial elements has a safety catch configured to stop the tab at a predetermined location so as to prevent further sliding of the tab within the slot.

8. The slide-and-lock stent of claim 1, wherein at least one of the slide-and-lock radial elements further comprises an actuating catch member configured to deflect from a non-actuated position to an actuated position and back again as it passes the lockout tooth during expansion.

9. The slide-and-lock stent of claim 8, further comprising a positive return element adapted to return said actuating catch to said non-actuated position after passing the lockout tooth.

10. The slide-and-lock stent of claim 8, wherein the lockout tooth further comprises a plurality of lockout teeth which are disposed along one side of the slot.

11. The slide-and-lock stent of claim 10, further comprising a plurality of positive return elements disposed along the other side of the slot from the lockout teeth and positioned so as to return said actuating catch to said non-actuated position after passing each of the plurality of lockout teeth.

12. The slide-and-lock stent of claim 1, wherein at least one of the radial elements further comprises a deformable region, such that radial expansion may occur through both sliding of circumferentially adjacent radial elements and deformation of the deformable region.

13. The slide-and-lock stent of claim 1, wherein an engaging tab is deflectable.

14. The slide-and-lock stent of claim 1, further comprising a linkage region within a module, wherein said linkage region is configured to facilitate material flexing.

15. The slide-and-lock stent of claim 14, wherein the linkage region includes a structural feature selected from the group consisting of a U-shaped member, inverted U-shaped member pairs, serpentine waves, linear connectors disposed at an angle to the longitudinal and circumferential axes, and undulating spring elements.

29. The slide-and-lock stent of claims 1, 16, 18, 20 or 28, wherein the longitudinally adjacent radial elements are connected to one another by a flexible linkage element.

34. The slide-and-lock stent of claims 1, 16, 18, 20, 28, 30 or 31, wherein a cross-sectional geometry of at least a portion of the stent is tapered so as to produce generally desirable blood flow characteristics when the stent is placed in a blood vessel lumen.

35. The slide-and-lock stent of claims 1, 16, 18, 20, 28, 30 or 31, wherein the stent further comprises a material selected from the group consisting of metal and polymer.

36. The slide-and-lock stent of claim 35, wherein the polymer comprises a bioresorbable polymer.

37. The slide-and-lock stent of claim 35, wherein the polymer comprises a radiopaque bioresorbable polymer.

38. The slide-and-lock stent of claim 35, wherein the polymer forms a coating on at least a portion of the stent.

39. The slide-and-lock stent of claim 38, wherein the polymer coating further comprises a biocompatible, bioresorbable polymer adapted to promote a selected response.

40. The slide-and-lock stent of claim 38, wherein the layered material comprises a bioresorbable polymer.

41. The slide-and-lock stent of claims 1, 16, 18, 20, 28, 30 or 31, wherein the stent further comprises at least two materials.

42. The slide-and-lock stent of claim 41, wherein the at least two materials comprise a structural configuration selected from the group consisting of materials that are stacked in the radial axis, materials that vary along the longitudinal axis, mixed materials, fused materials, coated materials, and materials that vary among structurally distinct elements.

43. The slide-and-lock stent of claims 1, 16, 18, 20, 28, 30 or 31, wherein the stent further comprises a therapeutic agent.

44. The slide-and-lock stent of claims 1, 16, 18, 20, 28, 30 or 31, further comprising a retractable sheath sized for enclosing the tubular member during delivery to a treatment site.

45. The slide-and-lock stent of claims 1, 16, 18, 20, 28, 30 or 31, further comprising a solid wall region.

46. The slide-and-lock stent of claim 45, wherein said solid wall region further comprises an opening.

47. The slide-and-lock stent of claims 1, 16, 18, 20, 28, 30 or 31, further comprising a polymeric sheath.

48. A system for treating a site within a vessel, comprising a catheter having a deployment means, and any stent of claims 1, 16, 18, 20, 28, 30 or 31, wherein said catheter is adapted to deliver the stent to said site and said deployment means is adapted to deploy the stent.

49. The system of claim 48, wherein said catheter is selected from the group consisting of over-the-wire catheters, coaxial rapid-exchange catheters, and multi-exchange delivery catheters.

50. The system of claim 48, wherein the stent further comprising a coating adapted to alter a physical characteristic of the stent.

51. The system of claim 50, wherein said coating is further adapted to form frangible bonds between the stent and said catheter, such that the stent is retained on said catheter until deployed.

52. A method for re-treatment of a body lumen, comprising the steps of:

deploying to a region of said body lumen any stent of claims 1, 16, 18, 20, 28, 30 or 31, wherein said stent is made from a bioresorbable polymer, and resides at said region for a period of time; and

administering to said region, after the period of time, a second treatment.

16. A slide-and-lock stent, comprising a tubular member having longitudinal and circumferential axes, said tubular member comprising:

a first radial element comprising an actuating rail having an actuator disposed thereron;

a second radial element, circumferentially adjacent to the first radial element, and slidably engaged with the first radial element, the second radial element comprising a deflectable catch element; and

a lockout catch,

wherein the actuator is configured so that as the second radial element slides relative to the first radial element, the actuator deflects the deflectable catch element thereby engaging the lockout catch, such that said tubular member achieves expansion in the circumferential axis with reduced recoil.

17. The slide-and-lock stent of claim 16, wherein the lockout catch is disposed along a frame element which surrounds the first radial element.

18. A slide-and-lock stent, comprising a tubular member having longitudinal and circumferential axes, said tubular member comprising:

a first radial element comprising a deflectable rail having a lockout tooth disposed thereron; and

a second radial element, circumferentially adjacent to said first radial element, and slidably engaged with said first radial element, the second radial element comprising a slot,

wherein the slot is configured to slidably engage and deflect said deflectable rail as the lockout tooth disposed on the deflectable rail passes through the slot, such that said tubular member achieves expansion in the circumferential axis with reduced recoil.

19. The slide-and-lock stent of claim 18, wherein the deflectable rail further comprises two rails with a gap therebetween, wherein each rail has a plurality of lockout teeth disposed thereon.

20. A slide-and-lock stent, comprising a tubular member having longitudinal and circumferential axes, said tubular member comprising:

a first radial element comprising an elongate rail comprising a deflectable tooth; and

a second radial element, circumferentially adjacent to the first radial element, and comprising an engagement means configured to slidably engage said elongate rail of the first radial element and deflect said deflectable tooth as the tooth contacts said engagement means, such that said tubular member achieves expansion in the circumferential axis with reduced recoil.

21. The slide-and-lock stent of claim 20, wherein said engagement means comprises a locking tab configured to slide adjacent to said elongate rail in the longitudinal axis and deflect said tooth longitudinally toward said elongate rail.

22. The slide-and-lock stent of claim 20, wherein said engagement means comprises a locking tab configured to slide over or under said elongate rail and deflect said tooth toward the plane of said elongate rail.

23. The slide-and-lock stent of claim 20, wherein said engagement means comprises a closed loop which defines a slot.

24. The slide-and-lock stent of claim 23, wherein said elongate rail further comprises two rail members with a gap therebetween, such that the rail members are configured to deflect toward one another into the gap when engaged by said slot.

25. The slide-and-lock stent of claim 20, wherein said elongate rail has a plurality of deflectable teeth disposed thereon.

26. The slide-and-lock stent of claim 20, further comprising a first module comprising more than one of the first radial elements, linked to one another in the longitudinal axis, and second module comprising more than one of the second radial elements, linked to one another in the longitudinal axis.

27. The slide-and-lock stent of claim 26, wherein the longitudinally linked radial elements in each module are circumferentially offset from one another in a zig-zig pattern.

28. A slide-and-lock stent, comprising a tubular member having longitudinal and circumferential axes, said tubular member comprising:

a first radial element comprising a first serrated surface; and

a second radial element, circumferentially adjacent to and slidably engaged with said first radial element, and comprising a second serrated surface,

wherein the first and second serrated surfaces engage one another in a complimentary hill and valley configuration adapted to resist sliding, whereby once expanded by application of radial force, said tubular member resists recoil.

30. A slide-and-lock stent, comprising a tubular member having longitudinal and circumferential axes, said tubular member comprising:

a first module comprising at least two circumferentially offset slide-and-lock radial elements and a coupling element, wherein each radial element comprises a tab, a gap comprising lockout teeth, and a slot; and

a second module configured substantially identical to said first module and circumferentially adjacent to said first module,

wherein the radial elements from said second module are slidably engaged within the slots of the corresponding radial elements from said first module, and wherein the tabs of the radial elements from said second module are slidably engaged within the gaps of the corresponding radial elements from said first module, such that the lockout teeth engage the tabs to minimize recoil.

31. A slide-and-lock stent, comprising a tubular member having longitudinal and circumferential axes, said tubular member comprising:

first and second longitudinal modules, each comprising peaks and valleys, wherein a protrusion comprising a lockout tooth extends from a first peak in each module, and a slot extends through a location along a second peak in each module, wherein the protrusion from the first module is slidably engaged within the slot from the second module.

32. The slide-and-lock stent of claim 31, wherein the modules comprise (n) material layers, wherein (n) is at least two.

33. The slide-and-lock stent of claim 32, wherein the protrusion and the location each comprise less than (n) material layers, and wherein the total number of material layers at the location equals (n) when the protrusion from the first module is slidably engaged within the slot from the second module, such that the thickness of the slide-and-lock stent is uniform and does not exceed (n) layers.