System and method for analysis of neurological condition

• US 20060136806A1
• Filed: 12/20/2005
• Published: 06/22/2006
• Est. Priority Date: 12/22/2004
• Status: Abandoned Application

• Current Assignee: Pharmacyclics LLC (Abbvie Incorporated)
• Original Assignee: Pharmacyclics Incorporated (Abbvie Incorporated)
• Inventors: Smith, Jennifer, Harris, Brad J., Phan, See-Chun
• Application Number:
  US11/313,535
• Publication Number:
  US 20060136806A1
• Time in Patent Office: Days
• US Class Current: 715/205
• CPC Class Codes: A61B 5/16 Devices for psychotechnics using teaching or educational appliances G09B1/00 - G09B7/00; Testing reaction times ; Devices for evaluating the psychological state
• CPC Class Codes: A61B 5/165 Evaluating the state of mind, e.g. depression, anxiety
• CPC Class Codes: A61B 5/7445 Display arrangements, e.g. multiple display units
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients

Abstract

Embodiments of the present invention comprise computer-based tools facilitating visualization and assessment of progression of neurological disorders in a patient. In one embodiment, data is received in the form of the results of standardized neurological examination of the patient. This input is compared to a rule set defining progression of the disorder, and the results of this comparison are displayed in an electronic document featuring internal links. The data may be displayed as tables and/or charts, with elapsed time plotted along a row/column or axis, respectively. Progression indication may be displayed through changed color. The electronic document can also display data not directly relevant to neurological condition, for example medication and radiation treatment schedules. By automatically displaying the data and the derived progression assessment according to the rule set, embodiments of the present invention are of particularly use in rapidly and uniformly evaluating treatment therapies.

Claims

1. A method of displaying information regarding progression of a neurological disorder, the method comprising:

receiving as an input to a processor,

a first datum of a first type relevant to neurological state of a patient at a first time, and

a second datum of the first type relevant to neurological state of the patient at a second time subsequent to the first time;

causing the processor to apply a rule set to the first datum and the second datum to provide an indication of progression of the neurological disorder; and

causing the processor to generate an electronic document including the indication.

2. The method of claim 1 wherein the indication is displayed in the document by a difference in color between the first datum and the second datum.

3. The method of claim 2 wherein the first and second datum are displayed in the document as a points in a graph having time as an axis.

4. The method of claim 2 wherein the first and second datum are displayed in the document as a table having a row header labeled as the first type.

5. The method of claim 4 wherein the row header is linked to a graph having time as an axis and displaying the first and second datum as points.

6. The method of claim 1 wherein:

the processor further receives,

a first datum of a second type relevant to neurological state of a patient at a third time, and

a second datum of the second type relevant to neurological state of the patient at a fourth time subsequent to the third time;

the first and second datum of the second type are compared to the rule set by the processor to provide an additional indication of progression the neurological disorder; and

the document includes the additional indication.

7. The method of claim 6 wherein the indication is displayed by a difference in color between the first and second data of the first and second types.

8. The method of claim 7 wherein the first and second data of the first type are displayed on a first screen as a points in a first graph having time as an axis, and wherein the first and second data of the second type are displayed on a second screen as points in a second graph also having time as an axis.

9. The method of claim 7 wherein the first and second data of the first type are displayed in a first row of a table having a first row header labeled as the first type, and the first and second data of the second type are displayed in a second row of the table having a second row header labeled as the second type.

10. The method of claim 9 wherein:

the first and second types are related; and

the first and second row headers are linked to a screen displaying a first graph having time as an axis and including the first and second data of the first type as points, and a second graph also having time as an axis and including the first and second data of the second type as points.

11. The method of claim 6 wherein the rule set is configured to distinguish between a major progression criterion and a minor progression criterion.

12. The method of claim 1 wherein the processor is configured to display the indication as a first color change revealing a tentative conclusion of progression, and as a second color revealing a confirmation of progression.

13. An electronic document for visualizing progression of a neurological disorder in an individual patient, the electronic document comprising:

a contents page including a first link to a table of neurological symptoms;

a table of neurological symptoms page including a second link to a graphical display, wherein a progression of the neurological disorder is indicated by a change in color between a first data entry into the table and a second data entry into the table; and

a graphical display page wherein the progression of the neurological disorder is indicated by the change in color between a first data point plotted on a chart and a second data point plotted on the chart.

14. The electronic document of claim 13 wherein the contents page further comprises a third link to a page displaying other than a neurological symptom.

15. The electronic document of claim 13 wherein the graphical display page further comprises a second chart plotting a third data point and a fourth data point.

16. The electronic document of claim 15 wherein the graphical display page further comprises a third link to supplemental graphical display page including one of the first chart and the second chart.

17. The electronic document of claim 13 recorded on a storage medium in a format selected from the group comprising jpg, tiff, giff, html, pdf, doc, rtf, and dhtml.

18. A computer readable storage medium having a computer-readable program embodied therein for directing operation of a host computer including an input/output system, and a processor, wherein the computer-readable program includes instructions for operating the host computer to process medical information according to the following:

receiving a first datum of a first type relevant to neurological state of a patient at a first time;

receiving a second datum of the first type relevant to neurological state of the patient at a second time subsequent to the first time;

applying a rule set to the first datum and the second datum to provide an indication of progression the neurological disorder; and

causing the processor to generate an electronic document including the indication.

19. The computer readable storage medium of claim 18 wherein the computer readable program includes instructions to cause the processor to generate the electronic document comprising a plurality of electronically linked pages including a contents page and a graphics display page.

20. The computer readable storage medium of claim 18 wherein the computer readable program includes instructions to cause the processor to generate the electronic document in a format selected from the group comprising jpg, tiff, giff, html, pdf, doc, rtf, and dhtml.