Tissue scaffold
First Claim
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1. A tissue scaffold comprising:
- a first film including a plurality of cell openings; and
a second film adjacent the first film and including a plurality of cell openings larger than the cell openings of the first film;
wherein the cell openings of the first film interconnect with the cell openings of the second film to define pathways extending from the first film to the second film.
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Abstract
A tissue scaffold includes a first film having a plurality of cell openings and a second film adjacent the first film and having a plurality of cell openings larger than the cell openings of the first film. The cell openings of the first film interconnect with the cell openings of the second film to define pathways extending through the first and second films.
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Citations
20 Claims
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1. A tissue scaffold comprising:
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a first film including a plurality of cell openings; and
a second film adjacent the first film and including a plurality of cell openings larger than the cell openings of the first film;
wherein the cell openings of the first film interconnect with the cell openings of the second film to define pathways extending from the first film to the second film. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method of repairing tissue, the method comprising:
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applying a scaffold to a tissue, the scaffold comprising a first film including a plurality of cell openings and a second film adjacent the first film and including a plurality of cell openings larger than the cell openings of the first film, the cell openings of the first film interconnecting with the cell openings of the second film to define pathways extending through the first and second films; and
positioning a plurality of delivery channels extending from the first film to the second film to a predetermined region of the tissue. - View Dependent Claims (16, 17)
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18. A method of making a tissue scaffold, the method comprising:
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forming cell openings in a first film to define a first porosity;
forming cell openings in a second film to define a second porosity greater than the first porosity;
aligning the first film with respect to the second film; and
attaching the first and second films such that the cell openings of the first film interconnect with the cell openings of the second film to define pathways extending from the first film to the second film. - View Dependent Claims (19)
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20. A tissue scaffold comprising:
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a first film including a first porosity; and
a second film joined to the first film and including a second porosity greater than the first porosity; and
a plurality of delivery channels extending through the first and second films;
wherein the first porosity and the second porosity define a porosity gradient extending from the first to the second film to selectively promote cellular regeneration along the gradient.
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Specification