Visible-near infrared spectroscopy in burn injury assessment
First Claim
1. A method of characterizing a burn comprising:
- emitting a beam of near infrared light into a burnt tissue portion to a first depth;
collecting and analyzing reflected light from the beam, thereby producing a first depth spectrum;
emitting a beam of near infrared light into a burnt tissue portion to a second depth;
collecting and analyzing reflected light from the beam, thereby producing a second depth spectrum;
comparing the first depth spectrum and the second depth spectrum; and
categorizing the burn based on said comparison.
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Abstract
A non-invasive method of characterizing burn injuries using near infrared spectroscopy is described. In the method, a beam of light is emitted into the burnt tissue portion at two or more different tissue depths. The spectra are then compared using multivariate analysis to determine diagnostic regions of the spectra. This information is used to categorize the burn. In some cases, the diagnostic regions correspond to wavelengths related to the hemodynamics of the tissue portion. The spectra can also be repeated over time, thereby allowing trends and changes in the spectra to be measured. This data is in turn used to categorize the burn as either a superficial burn, partial thickness burn, deep partial burn or a full thickness burn. Once the burn has been categorized, the clinician can intervene as needed to treat the burn.
197 Citations
11 Claims
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1. A method of characterizing a burn comprising:
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emitting a beam of near infrared light into a burnt tissue portion to a first depth;
collecting and analyzing reflected light from the beam, thereby producing a first depth spectrum;
emitting a beam of near infrared light into a burnt tissue portion to a second depth;
collecting and analyzing reflected light from the beam, thereby producing a second depth spectrum;
comparing the first depth spectrum and the second depth spectrum; and
categorizing the burn based on said comparison. - View Dependent Claims (2, 3, 4)
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5. A method of characterizing a burn comprising:
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at a first time point;
(a) emitting a beam of near infrared light from into a burnt tissue portion at a first tissue depth;
(b) collecting and analyzing reflected light from the beam, thereby producing an early first depth spectrum;
(c) emitting a beam of near infrared light from into a burnt tissue portion at a second tissue depth;
(d) collecting and analyzing reflected light from the beam, thereby producing an early second depth spectrum;
at a second time point;
(e) emitting a beam of near infrared light from into a burnt tissue portion at said first tissue depth;
(f) collecting and analyzing reflected light from the beam, thereby producing a late first depth spectrum;
(g) emitting a beam of near infrared light from into a burnt tissue portion at said second tissue depth;
(h) collecting and, analyzing reflected light from the beam, thereby producing a late second depth spectrum; and
characterizing said burnt tissue portion based on spectral changes over time at said first and second tissue depths. - View Dependent Claims (6, 7, 8, 9, 10, 11)
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Specification