Three-dimensional implantable bone support

• US 20060155296A1
• Filed: 01/09/2006
• Published: 07/13/2006
• Est. Priority Date: 01/07/2005
• Status: Abandoned Application

• Current Assignee: Celonova Biosciences, Inc. (Boston Scientific Corporation)
• Original Assignee: Celonova Biosciences, Inc. (Boston Scientific Corporation)
• Inventors: Richter, Goetz Martin
• Application Number:
  US11/328,345
• Publication Number:
  US 20060155296A1
• Time in Patent Office: Days
• US Class Current: 606/94
• CPC Class Codes: A61B 17/7097 Stabilisers comprising fluid filler in an implant, e.g. balloon; devices for inserting or filling such implants disc prostheses made of inflatable chambers or pockets filled with fluid A61F2/441; replacing the nucleus pulposus A61F2002/444
• CPC Class Codes: A61P 19/00 Drugs for skeletal disorders
• CPC Class Codes: A61P 19/10 for osteoporosis
• CPC Class Codes: A61P 35/00 Antineoplastic agents
• CPC Class Codes: A61P 35/04 specific for metastasis
• CPC Class Codes: A61P 5/00 Drugs for disorders of the endocrine system
• CPC Class Codes: A61P 9/10 for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

The present invention relates to an expandable semi-compliant device that may be used for the treatment of diseased or injured bone tissues, and a method of using the same. The semi-compliant device is inserted into the interior space of a cancellous bone tissue, and is filled with a suitable material to provide internal structural support to the bone. The semi-compliant device may also act as a carrier for medicinal, radiological, or thermal treatments of the diseased bone.

Claims

1. A method of treating diseased or injured bone tissue comprising:

selecting an interior area in a bone tissue to be treated;

inserting a device into the interior area of the bone tissue to be treated; and

internally supporting the bone tissue using the device during treatment.

2. The method according to claim 1, further comprising selecting the interior area using a minimally invasive image-guided technique.

3. The method according to claim 1, wherein the device is replaceable.

4. The method according to claim 3, wherein the device is a catheter having a structure capable of supporting the bone tissue.

5. The method according to claim 4, wherein the catheter comprises an expandable three-dimensional, semi-compliant structure and fastener, and wherein the fastener releasably connects the catheter to the semi-compliant structure.

6. The method according to claim 5, wherein the catheter is detachable from the semi-compliant structure.

7. The method according to claim 6, wherein the catheter has a main body defining at least one interior passage therethrough, the semi-compliant structure defines an interior space, and the semi-compliant structure comprises a sealable port that allows for communication between the interior passage of the catheter and the interior space of the semi-compliant structure.

8. The method according to claim 7, further comprising injecting a bone supporting material into the semi-compliant structure through the passage within the catheter, through the sealable port, and into the interior space of the structure, thereby expanding the three-dimensional semi-compliant structure within the bone tissue.

9. The method according to claim 8, wherein the bone supporting material is capable of hardening to provide permanent bone support for the bone tissue.

10. The method according to claim 8, further comprising:

admixing a radiological treatment material with the bone supporting material to form an admixture and introducing the admixture into the semi-compliant structure, wherein the semi-compliant structure is capable of facilitating exposure of the area to be treated to the radiological material; and

exposing the bone tissue to the radiological treatment.

11. The method according to claim 10, further comprising replacing the semi-compliant structure with a second, replacement three-dimensional semi-compliant structure when the radiological treatment is depleted.

12. The method according to claim 10, wherein the radiological treatment is a time-release medication, and the medication may exfiltrate the semi-compliant structure and coat the surface of the semi-compliant structure.

13. The method according to claim 10, wherein the semi-compliant structure comprises a semi-permeable material and the medication diffuses through the semi-permeable material to treat a disease or injury.

14. The method according to claim 13, wherein the semi-permeable material is selected from the group consisting of polymeric materials, resorbable synthetic material, suture material, Nitinol, and combinations thereof.

15. The method according to claim 14, wherein the material is a biocompatible Nitinol.

16. The method according to claim 14, wherein the polymeric material is selected from the group consisting of polyesters, polyethylenes, polylactic acids, and combinations thereof.

17. The method according to claim 13, wherein the disease or injury is selected from the group consisting of osteoporosis, osteoporotic fractured metaphyseal and epiphyseal bone, osteoporotic vertebral bodies, fractures of vertebral bodies due to tumors, round cell tumors, avascular necrosis of the epiphyses of long bones, avascular necrosis of the proximal femur, distal femur and/or proximal humerus, defects arising from endocrine conditions, metastatic tumors, and combinations thereof.

18. The method according to claim 8, wherein the semi-compliant structure is detachable from the catheter, and the method further comprises:

detaching the catheter from the semi-compliant structure;

sealing the sealable port; and

maintaining the bone supporting material within the structure in a pressurized environment, thereby preventing the bone supporting material from exuding from within the structure, to provide temporary support of the bone tissue.

19. The method according to claim 8, wherein the bone supporting material is selected from the group consisting of a liquid, paste, gel, cement, and combinations thereof.

20. The method according to claim 19, wherein the bone supporting material is a cement.

21. The method according to claim 20, wherein the cement comprises a material selected from the group consisting of polymethylmethacrylate, dextran, polyethylene, carbon fiber, polyvinyl alcohol, and poly(ethylene terephthalate).

22. The method according to claim 19, wherein the bone supporting material is a liquid.

23. The method according to claim 18, further comprising:

reattaching the catheter to the sealable port; and

withdrawing the bone supporting material.

24. A device for treating diseased or injured bone comprising:

a catheter, wherein the catheter comprises a main body defining at least one interior passage therethrough;

an expandable semi-compliant structure, wherein the semi-compliant structure defines an interior space; and

a removable fastener, wherein the fastener removably connects the catheter to the semi-compliant structure.

25. The device according to claim 24, further comprising a sealable port, through which the interior passage of the catheter communicates with the interior space of the semi-compliant structure.

26. The device according to claim 25, wherein the catheter is detachable from the semi-compliant structure.

27. The device according to claim 26, wherein the catheter is capable of receiving bone supporting material.

28. The device according to claim 24, wherein the fastener is a screw device.

29. The device according to claim 24, wherein the semi-compliant structure is capable of expanding to adapt an area to be treated in a bone.