Microfluidic device
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Abstract
A microfluidic device adapted such that the flow of fluids within the device is controlled by different surfaces of the device having different surface characteristics. Preferably the device comprises a substrate not formed from a hydrated oxide material.
108 Citations
41 Claims
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1-19. -19. (canceled)
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20. A microfluidic device comprising:
a circular device which is adapted for rotation about its axis and comprises two substrates between which there are predetermined hydrophilic pathways for liquid flow, and a hydrophobic section within in a hydrophilic pathway to form a valve that provides a break in liquid flow passing through the pathway. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A method of producing a microfluidic device having the form of a disc which is adapted for rotation about an axis, and comprising two substrates at least one of which controls flow of a liquid in the microfluidic device comprising the step of:
treating at least one substrate such that the surface of the treated substrate comprises hydrophilic pathways for liquid flow of the liquid and a hydrophobic section or valve within a hydrophilic pathway to prevent flow of the liquid. - View Dependent Claims (32, 33, 34, 35)
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36. A method for controlling flow of a liquid in a microfluidic device comprising the steps of:
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providing a microfluidic device which is adapted for rotation about an axis and comprises two substrates between which there are predetermined hydrophilic pathways for liquid flow, and a hydrophobic section within a hydrophilic pathway to form a valve that provides a break in liquid flow passing through the pathway adding the liquid to an inlet of the microfluidic device, wherein the liquid flows down the hydrophilic pathway until the liquid reaches the hydrophobic section or valve within the pathway preventing the flow of liquid; and
applying sufficient energy to the liquid allowing it to pass the valve and continue to flow down the pathway. - View Dependent Claims (37, 38, 39, 40, 41)
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Specification