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Compositions and methods for treating coagulation related disorders

  • US 20060159675A1
  • Filed: 12/19/2005
  • Published: 07/20/2006
  • Est. Priority Date: 06/19/2003
  • Status: Abandoned Application
First Claim
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1. A method for preventing or treating a sepsis or inflammatory disease in a mammal, the method comprising administering to the mammal a therapeutically effective amount of at least one humanized antibody, chimeric antibody, or fragment thereof that binds specifically to tissue factor (TF) to form a complex, wherein factor X or factor IX binding to the complex is inhibited and the administration is sufficient to prevent or treat the sepsis in the mammal.

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