Methods and compositions for polypeptide engineering
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Abstract
Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
74 Citations
277 Claims
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1-273. -273. (canceled)
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274. A method of producing mutagenized polypeptides containing a selectable feature comprising the steps of:
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a) mutagenizing polypeptides containing a selectable feature to produce diversely mutagenized polypeptides;
b) selecting from the diversely mutagenized polypeptides those containing the selectable feature; and
thereby producing the mutagenized polypeptides containing the selectable feature. - View Dependent Claims (275, 276, 277)
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Specification