Device and method for analyte detection
First Claim
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1. A device comprising:
- a multi-layered substrate, the multi-layered substrate comprising a first layer and a coated metal layer, the coated metal layer comprising a heat-conducting metal layer and a plastic polymer coating on the heat-conducting metal layer for preventing corrosion of the heat-conducting metal layer, wherein the first layer and the coated metal layer are sealably bonded together;
a sample-distribution network defined by the multi-layered substrate and comprising (i) a sample inlet, (ii) two or more detection chambers, and (iii) channels providing dead-end fluid connections between the detection chambers and the inlet; and
detection reagents in the detection chambers.
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Abstract
The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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Citations
1 Claim
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1. A device comprising:
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a multi-layered substrate, the multi-layered substrate comprising a first layer and a coated metal layer, the coated metal layer comprising a heat-conducting metal layer and a plastic polymer coating on the heat-conducting metal layer for preventing corrosion of the heat-conducting metal layer, wherein the first layer and the coated metal layer are sealably bonded together;
a sample-distribution network defined by the multi-layered substrate and comprising (i) a sample inlet, (ii) two or more detection chambers, and (iii) channels providing dead-end fluid connections between the detection chambers and the inlet; and
detection reagents in the detection chambers.
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Specification