System and method for detecting artifactual hemodynamic waveform data

• US 20060167360A1
• Filed: 01/27/2005
• Published: 07/27/2006
• Est. Priority Date: 01/27/2005
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Choi, Mark, Whitman, Teresa A., Bennett, Tommy D., Hill, Michael R.S., Igel, David A.
• Granted Patent: US 7,708,693 B2
• Time in Patent Office: Days
• US Class Current: 600/485
• CPC Class Codes: A61B 5/02108 from analysis of pulse wave characteristics
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00

Abstract

A system and method for cardiovascular analysis includes an implantable medical device capable of generating hemodynamic pressure waveform data based upon sensed pressure. Hemodynamic waveform data is analyzed to identify artifactual data represented in the hemodynamic waveform.

Claims

1. A cardiovascular analysis system, comprising:

a sensor adapted to sense a hemodynamic pressure over time in cooperation with a transmitter;

an implantable medical device for generating hemodynamic pressure waveform data based upon the hemodynamic pressure sensed; and

means for analyzing the hemodynamic waveform data to identify artifactual data represented in the hemodynamic waveform data.

2. A system according to claim 1, wherein the means for analyzing the hemodynamic waveform data is contained in the implantable medical device.

3. A system according to claim 1 and further comprising means for generating trend data based upon the hemodynamic waveform data.

4. A system according to claim 3, wherein the trend data is filtered based upon artifactual data identified in the hemodynamic pressure waveform data.

5. A system for hemodynamic waveform data analysis, the system comprising:

means for generating hemodynamic pressure waveform data that corresponds to sensed hemodynamic pressure over time;

means for analyzing the hemodynamic pressure waveform data to determine hemodynamic waveform parameters, including a systolic pressure and a diastolic pressure for a cardiovascular pulse cycle; and

means for detecting the presence of artifactual data in a series of hemodynamic waveforms based upon profiles of each hemodynamic waveform in the series.

6. A system according to claim 5, wherein the means for detecting the presence of any artifactual data is capable of identifying hemodynamic pressure waveform data containing artifactual data.

7. A system according to claim 5 and further comprising means for generating trend data based upon the hemodynamic pressure data.

8. A system according to claim 7 and further comprising means for excluding from the trend data any hemodynamic pressure waveform data for a cardiovascular pulse cycle containing artifactual data.

9. A system according to claim 5 and further comprising means for excluding artifactual data from hemodynamic waveform data containing the artifactual data.

10. A system according to claim 5 and further comprising means for creating dP/dt plots representative of the first derivatives of the hemodynamic pressure waveform data with respect to time, and determining maximum and minimum values for each dP/dt plot.

11. A system according to claim 10, wherein the artifactual data corresponds to any maximum dP/dt value greater than a predetermined value.

12. A system according to claim 11, wherein the predetermined value has a magnitude of about 512 mmHg/sec.

13. A system according to claim 5, wherein hemodynamic pressure waveform data having a pulse width less than a predetermined time period are identified as containing artifactual data.

14. A system according to claim 13, wherein the predetermined time period has a magnitude of about 74.2 milliseconds.

15. A system according to claim 5, wherein hemodynamic pressure waveform data having a negative average pressure value is identified as containing artifactual data.

16. A system according to claim 5, wherein hemodynamic pressure waveform data having a diastolic pressure value greater than a predetermined value is identified as containing artifactual data.

17. A system according to claim 16, wherein the predetermined value is about 50 mmHg.

18. A system according to claim 5, wherein hemodynamic pressure waveform data having a substantially constant pressure value for longer than a predetermined time during a designated period of pressure sensing is identified as containing artifactual data.

19. A system according to claim 18, wherein the predetermined time is about 78 milliseconds, and wherein the designated period of pressure sensing is from about zero to about 150 milliseconds of pressure sensing.

20. A system according to claim 18, wherein the predetermined time is about 150 milliseconds, and wherein the designated period of pressure sensing is from about 200 to about 400 milliseconds of pressure sensing.

21. A system according to claim 5, wherein the hemodynamic pressure waveform data includes a first sample and a last sample, and wherein any hemodynamic pressure waveform data having first and last samples with pressure values that differ by more than a predetermined value are identified as containing artifactual data.

22. A system according to claim 21, wherein the predetermined value is about 30 mmHg.

23. A method of hemodynamic waveform data analysis, the method comprising:

sensing a hemodynamic pressure for a pulse cycle using an implantable medical device;

generating hemodynamic pressure waveform data based upon the hemodynamic pressure sensed; and

analyzing the hemodynamic pressure waveform data for the presence of artifactual waveform data.

24. A method of hemodynamic waveform data analysis, the method comprising:

sensing hemodynamic pressure for a pulse cycle using an implantable medical device;

generating hemodynamic pressure waveform data based upon the hemodynamic pressure sensed; and

compiling trend data based upon the hemodynamic waveform data adjusted according to a presence of artifactual data, when artifactual data is present in the hemodynamic pressure waveform data.

25. The method of claim 24, wherein the trend data is adjusted to exclude all hemodynamic pressure waveform data for a cardiovascular pulse cycle that contains artifactual data.

26. The method of claim 24, wherein the trend data is adjusted to identify a presence of artifactual data.