Blood perfusion system

• US 20060167400A1
• Filed: 01/17/2006
• Published: 07/27/2006
• Est. Priority Date: 09/27/2000
• Status: Active Grant

• Current Assignee: Sorin Group USA Incorporated (LivaNova Plc)
• Original Assignee: Cobe Cardiovascular Incorporated (LivaNova Plc)
• Inventors: Ingebrigtsen, J Steven, Carson, Cary A., Kappus, John J., Lawrence, Bruce E., Kollar, Kevin J., Schwab, Mike E., Dalke, William D., Ellingboe, Bruce S.
• Granted Patent: US 8,057,419 B2
• Time in Patent Office: Days
• US Class Current: 604/6.140
• CPC Class Codes: A61M 1/32 Oxygenators without membranes
• CPC Class Codes: A61M 1/322 Antifoam; Defoaming
• CPC Class Codes: A61M 1/3613 Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
• CPC Class Codes: A61M 1/3621 Extra-corporeal blood circuits single-needle circuits A61M1/30
• CPC Class Codes: A61M 1/362227 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/36226 Constructional details of cassettes, e.g. specific details on material or shape
• CPC Class Codes: A61M 1/362262 Details of incorporated reservoirs
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: A61M 1/3624 Level detectors; Level control
• CPC Class Codes: A61M 1/3626 Gas bubble detectors
• CPC Class Codes: A61M 1/3632 Combined venous-cardiotomy reservoirs
• CPC Class Codes: A61M 1/3639 Blood pressure control, pressure transducers specially adapted therefor
• CPC Class Codes: A61M 1/3641 Pressure isolators
• CPC Class Codes: A61M 1/3643 Priming, rinsing before or after use
• CPC Class Codes: A61M 1/3644 Mode of operation
• CPC Class Codes: A61M 1/3663 Flow rate transducers; Flow integrators
• CPC Class Codes: A61M 1/3664 for preparing cardioplegia solutions
• CPC Class Codes: A61M 1/3666 Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
• CPC Class Codes: A61M 1/3667 with assisted venous return
• CPC Class Codes: A61M 2205/123 : with incorporated reservoirs
• CPC Class Codes: A61M 2205/128 : with incorporated valves
• CPC Class Codes: A61M 2205/3389 : Continuous level detection A61M2205/3393 takes precedence
• CPC Class Codes: A61M 2205/505 : Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
• CPC Class Codes: A61M 2205/705 : Testing of filters for leaks
• CPC Class Codes: A61M 2205/707 : Testing of filters for clogging
• CPC Class Codes: A61M 2209/082 : Mounting brackets, arm supports for equipment

Abstract

An extracorporeal blood perfusion system includes a disposable assembly and a control unit having a control interface region. The interface region includes pump assemblies for selective pumping of venous blood, arterial blood, cardioplegia solution, suctioned blood and blood removed from the left ventricle. Valve assemblies control the flow of fluids through the assembly and to/from the patient and sensors monitor various fluid parameters including temperature and pressure within the various fluid circuits. The user interface is a functional screen interface for effecting the operation of the control unit and valve assemblies. The screen interface may be a touch screen having objects that corresponds to the component interface region. The display may be selectively controlled to provide graphic depictions of disposable assembly components with corresponding narrative instructions.

Claims

1. In an extracorporeal blood perfusion system for receiving blood from a patient through a venous line, oxygenating the blood, and returning the oxygenated blood to the patient through an arterial line, a method of preventing the return of oxygenated blood containing gaseous bubbles to the patient, the extracorporeal blood perfusion system including a cardiopulmonary blood circuit having a plurality of tubing lines interconnecting a venous reservoir, a blood oxygenator and an arterial blood filter, the method comprising:

connecting the blood perfusion system for receiving venous blood from the patient and returning oxygenated blood to the patient;

providing an air purge line including a purge valve having an open position for opening the purge line and a closed position for closing the purge line;

fluidly connecting a first end of the purge line with an outlet of the oxygenator and a second end of the purge line with an inlet of the venous reservoir; and

providing a control unit having a sensor for determining the presence of gaseous bubbles in a tubing line connected to an outlet of the oxygenator, the control unit being connected to the first pump for controlling the speed of the first pump and being connected to the purge valve for automatically opening the purge valve when gaseous bubbles are sensed by the sensor such that at least a portion of the oxygenated blood is diverted from the patient through the air purge line back to the venous reservoir.

2. The method of claim 1 wherein the step of fluidly connecting the first and second ends of the purge line includes connecting the first end of the purge line to a purge port on the arterial blood filter.

3. The method of claim 1 further including providing an arterial valve in the arterial line, the arterial valve having an open position for opening the arterial line and a closed position for closing the arterial line and wherein the step of providing a control unit includes providing a control unit connected to the arterial valve for automatically closing the arterial valve when gaseous bubbles are sensed by the sensor.

4. The method of claim 1 wherein the step of providing a control unit includes providing a control unit connected to the first pump for automatically slowing the speed of the first pump when gaseous bubbles are sensed by the sensor.