Medical devices and methods of making the same

• US 20060167407A1
• Filed: 01/26/2005
• Published: 07/27/2006
• Est. Priority Date: 01/26/2005
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Weber, Jan, Spencer, Steven M.
• Granted Patent: US 8,202,245 B2
• Time in Patent Office: Days
• US Class Current: 604/103.20
• CPC Class Codes: A61L 27/50 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: A61L 29/14 Materials characterised by their function or physical properties , e.g. lubricating compositions
• CPC Class Codes: A61M 2025/1031 Surface processing of balloon members, e.g. coating or deposition; Mounting additional parts onto the balloon member's surface
• CPC Class Codes: A61M 25/0009 Making of catheters or other medical or surgical tubes
• CPC Class Codes: A61M 25/1029 Production methods of the balloon members, e.g. blow-moulding, extruding, deposition or by wrapping a plurality of layers of balloon material around a mandril

Abstract

Medical devices and methods of making the devices are described. In some embodiments, a method of making a medical device includes addressing a member including a polymer with energy above an ablation threshold of the polymer, and using the member to make the medical device.

Claims

1. A method of making a medical device, comprising:

addressing a member comprising a polymer with energy above an ablation threshold of the polymer; and

using the member to make the medical device.

2. The method of claim 1, wherein the energy has a fluence greater than about 40 mJ/cm².

3. The method of claim 1, wherein the energy is delivered from a laser.

4. The method of claim 3, further comprising pulsing the energy delivered from the laser.

5. The method of claim 1, wherein the addressed member is textured and comprises a raised portion having a height of about 0.5 micron.

6. The method of claim 1, wherein the member is a tubular member.

7. The method of claim 6, wherein the medical device comprises a medical balloon.

8. The method of claim 6, wherein the tubular member comprises a plurality of layers.

9. The method of claim 6, further comprising forming a first polymeric layer on the tubular member.

10. The method of claim 9, further comprising forming the tubular member into a catheter.

11. The method of claim 1, wherein the addressed member comprises a first portion and a second portion raised relative to the first portion, and the method further comprises placing a first therapeutic agent on the first portion, and placing a second therapeutic agent on the second portion.

12. The method of claim 1, wherein the medical device is a medical graft.

13. The method of claim 1, wherein the medical device is an endoprosthesis.

14. A medical device, comprising:

a surface comprising a plurality of first portions and a plurality of second portions raised relative to the first portions, the second portions having an average height of about 0.1 to about three microns.

15. The device of claim 14, wherein the surface is an outer surface.

16. The device of claim 14, wherein the surface is an interfacial surface between two layers of the medical device.

17. The device of claim 14, further comprising a first therapeutic agent on the first portions, and a second therapeutic agent on the second portions.

18. The device of claim 17, in the form of a medical graft.

19. The device of claim 14, comprising a tubular member comprising the surface, wherein the second portions extend generally transverse to a longitudinal axis of the tubular member.

20. The device of claim 14, in the form of the medical balloon.

22. The device of claim 14, in the form of a medical graft.

23. The device of claim 14, in the form of an endoprosthesis.

24. The device of claim 14, comprising a member comprising a polymer, the member defining the surface.

25. A method of making a medical device, comprising:

contacting a member comprising a polymer with a plasma to produce a surface on the member a plurality of first portions and a plurality of second portions raised relative to the first portions; and

using the member to make the medical device.

21. The device of claim 27, in the form of a catheter.

26. The method of claim 25, wherein the plasma comprises a material selected from the group consisting of oxygen and argon.

27. The method of claim 25, comprising contacting the member with the plasma at less than about 25°

C.

28. The method of claim 25, wherein the second portions have a height less than about a micron.

29. The method of claim 25, wherein the member comprises a polymer.

30. The method of claim 25, further comprising placing a first therapeutic agent on the first portions, and placing a second therapeutic agent on the second portions.

31. The method of claim 25, wherein the medical device is selected from the group consisting of a medical balloon, a catheter, an endoprosthesis, and a medical graft.