Device and method for improving upper airway functionality

• US 20060167523A1
• Filed: 11/10/2005
• Published: 07/27/2006
• Est. Priority Date: 10/15/2003
• Status: Abandoned Application

• Current Assignee: RMX, LLC (ASHINC Corp.)
• Original Assignee: RMX, LLC (ASHINC Corp.)
• Inventors: Province, Rose, Lee, Chang, Ligon, David, Tehrani, Amir J., Goodman, Amy Michelle
• Application Number:
  US11/272,353
• Publication Number:
  US 20060167523A1
• Time in Patent Office: Days
• US Class Current: 607/42
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/389 Electromyography [EMG]
• CPC Class Codes: A61B 5/395 Details of stimulation, e.g. nerve stimulation to elicit EMG response
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: A61N 1/3601 of respiratory organs

Abstract

A device and method is provided for improving upper airway functionality by electrically stimulating tissue associated with the diaphragm or phrenic nerve of a subject.

Claims

1. A device for treating a breathing related disorder comprising:

an implantable electrode configured to be implanted to stimulate tissue associated with a respiratory tract of a patient to cause a diaphragm response; and

an electrical stimulator coupled to the implantable electrode and programmed with an electrical stimulation protocol directed to increasing flow or tidal volume in order to stiffen an upper airway passage of a patient;

wherein the stimulator is electrical communication with the implantable electrode to thereby supply an electrically stimulating signal to the tissue according to the electrical stimulation protocol.

2. The device of claim 1 wherein the protocol comprises a deep inspiration protocol configured to provide stimulation to increase tidal volume of a breath above an intrinsic tidal volume.

3. The device of claim 2 wherein the protocol is further configured to provide a normalized peak flow

4. The device of claim 2 further comprising:

a stimulation timer configured to cause the electrically stimulating signal to occur during an inspiration portion of an intrinsic breath of the patient.

5. The device of claim 4 wherein the stimulation timer is configured to provide the electrically stimulating signal at least in part during an inspiration portion of an intrinsic breath.

6. The device of claim 4 wherein the stimulation timer is configured to provide the electrical stimulation at least in part during an exhalation portion of a respiration cycle.

7. The device of claim 4 wherein the stimulation timer is configured to provide the electrical stimulation during an end portion of an exhalation portion of a respiration cycle.

8. The device of claim 1 wherein the stimulation protocol comprises a protocol for periodically providing stimulation to the tissue.

9. A method of treating a breathing related disorder comprising:

providing an electrical stimulator ; and

electrically stimulating tissue associated with the respiratory tract of the patient to cause a diaphragm response to increase in overall air flow of a respiration cycle with respect to an intrinsic over all air flow of an intrinsic respiration cycle, in an upper airway of a patient prior to at least one subsequent inspiration cycle.

10. The method of claim 9 wherein the electrical stimulation protocol is directed to increasing tidal volume of a breath with respect to a tidal volume of an intrinsic breath of the patient.

11. The method of claim 9 wherein the step of electrically stimulating comprises electrically stimulating at least in part during an inspiration portion of an intrinsic breath of the patient.

12. The method of claim 9 wherein the stimulation protocol wherein the step of electrically stimulating comprises:

electrically stimulating asynchronously with respect to an inspiration portion of intrinsic breath of the patient.

13. A method of treating a breathing related disorder comprising the steps of:

providing an electrical stimulator configured to stimulate tissue associated with the phrenic nerve or diaphragm of a patient to elicit a diaphragm response;

stimulating the tissue during an inspiration cycle of an intrinsic breath to increase an inspiration duration of above a duration of a normal intrinsic breath.

14. The method of claim 13 wherein the step of stimulating tissue comprises stimulating tissue to normalize peak flow of a resulting breath with respect to the peak flow of the normal intrinsic breath.

15. A method of treating a breathing related disorder comprising the steps of:

providing an electrical stimulator configured to stimulate tissue associated with the phrenic nerve or diaphragm of a patient to elicit a diaphragm response;

stimulating the tissue during an inspiration cycle of an intrinsic breath to increase an tidal of above a tidal of a normal intrinsic breath.

16. The method of claim 15 wherein the step of stimulating tissue comprises stimulating tissue to normalize peak flow of a resulting breath with respect to the peak flow of the normal intrinsic breath.

17. A device for treating a breathing related disorder comprising:

an implantable electrode configured to be implanted to stimulate tissue associated with a respiratory tract of a patient to cause a diaphragm response; and

an electrical stimulator in electrical communication with the implantable electrode to thereby supply an electrically stimulating signal to the tissue and configured to increase an inspiration duration of a breath with respect to an inspiration duration of an intrinsic breath.

18. The device of claim 17 further comprising a stimulation timer configured to cause stimulation to occur during an inspiration portion of an intrinsic breath.