Medical Device and Method for Diagnostic Sensing
First Claim
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1. A device for use in medical diagnostics comprising:
- a substrate;
a plurality of discrete reservoirs located in the substrates each reservoir having at least one opening;
at least one diagnostic substance contained in each reservoir; and
at least one non-degradable barrier layer covering each reservoir opening, the barrier layer being permeable to an agent to be detected, wherein the diagnostic substance remains inside the reservoirs and can react with the agent to be detected.
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Abstract
Devices are provided for use in medical diagnostics which include a substrate, a plurality of discrete reservoirs located in the substrate, each reservoir having at least one opening, at least one diagnostic substance contained in each reservoir, and at least one non-degradable barrier layer covering each reservoir opening, the barrier layer being permeable to an agent to be detected, wherein the diagnostic substance remains inside the reservoirs and can react with the agent to be detected.
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Citations
16 Claims
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1. A device for use in medical diagnostics comprising:
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a substrate;
a plurality of discrete reservoirs located in the substrates each reservoir having at least one opening;
at least one diagnostic substance contained in each reservoir; and
at least one non-degradable barrier layer covering each reservoir opening, the barrier layer being permeable to an agent to be detected, wherein the diagnostic substance remains inside the reservoirs and can react with the agent to be detected. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. An implantable medical device for use in medical diagnostics comprising:
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a substrate;
a plurality of discrete reservoirs located in the substrate, each reservoir having at least one opening;
at least one diagnostic substance contained in each reservoir;
at least one non-degradable barrier layer covering each reservoir opening, the barrier layer being permeable to an agent to be detected, wherein the at least one non-degradable barrier layer comprises a semi-permeable polymeric membrane; and
at least one degradable barrier layer covering each reservoir opening, wherein the diagnostic substance remains inside the reservoirs and, following degradation of the at least one degradable barrier layer in vivo, can undergo a binding reaction with the agent to be detected. - View Dependent Claims (13, 14, 15, 16)
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Specification