Pharmaceutical formulation delivery system

• US 20060171970A1
• Filed: 03/01/2006
• Published: 08/03/2006
• Est. Priority Date: 02/21/2003
• Status: Abandoned Application

• Current Assignee: Cardio Combs, LLC
• Original Assignee: Cardio Combs, LLC
• Inventors: Karl, Mitchell S.
• Application Number:
  US11/365,563
• Publication Number:
  US 20060171970A1
• Time in Patent Office: Days
• US Class Current: 424/400
• CPC Class Codes: A61J 1/035 Blister-type containers blisters in general B65D75/36
• CPC Class Codes: A61J 7/0046 Cups, bottles or bags
• CPC Class Codes: A61J 7/0053 Syringes, pipettes or oral dispensers
• CPC Class Codes: A61J 7/04 Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
• CPC Class Codes: A61K 31/517 ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
• CPC Class Codes: A61K 9/0095 Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches A61K9/0007 takes precedence; eatable gels or foams A61K9/0056; oral mucosa adhesive forms A61K9/006

Abstract

The invention relates to the development of a simple and inexpensive oral delivery system for customized pharmaceutical formulations for treating patients having conditions such as HIV/AIDS, cancer, and heart disease. The system includes a) a plurality of prepackaged pharmaceutical formulations containing at least two pharmacologically active ingredients in periodic (e.g., daily, twice-daily, three times a day, four times a day) dosage amounts for treating a plurality of patients having differing characteristics and particular conditions to be treated, each formulation differing in pharmacologically active ingredients and/or dosage amounts from each other, and b) a chart listing the plurality of formulations for assisting a physician in deciding which formulation to administer to a patient suffering from a particular condition based on the patient'"'"'s characteristics. A customized pharmaceutical formulation that is suitable for a patient having a particular condition to be treated is easily selected by the physician from a paper or electronic chart listing a plurality of different pharmaceutical formulations and correlating the different formulations to different patient characteristics that should be considered before administering a pharmaceutical formulation to the patient.

Claims

1. A pharmaceutical formulation delivery system, the system comprising:

a) a plurality of prepackaged pharmaceutical formulations each comprising at least two pharmacologically active ingredients in periodic dosage amounts for treating a condition,

each pharmaceutical formulation differing in active ingredients or dosage amounts from each other; and

b) a chart listing at least a first set of patient characteristics relating to the condition and a second set of patient characteristics relating to the condition, the chart indicating a pharmaceutical formulation of the plurality of pharmaceutical formulations that is suitable for treating a patient having the first set or second set of patient characteristics.

2. The pharmaceutical formulation delivery system of claim 1, wherein at least one pharmaceutical formulation of the plurality of pharmaceutical formulations comprises at least three pharmacologically active ingredients in periodic dosage amounts for treating a condition.

3. The pharmaceutical formulation delivery system of claim 1, wherein the prepackaged pharmaceutical formulations are in liquid form.

4. The pharmaceutical formulation delivery system of claim 1, wherein at least one pharmaceutical formulation of the plurality of prepackaged pharmaceutical formulations is in liquid form and is prepackaged in a plastic receptacle for containing a liquid, the receptacle comprising a twist-off cap.

5. The pharmaceutical formulation delivery system of claim 1, wherein at least one pharmaceutical formulation of the plurality of prepackaged pharmaceutical formulations comprises a powder and a liquid and is prepackaged in a plastic receptacle, the plastic receptacle comprising a twist-off cap, a first compartment for containing the powder, and a second compartment for containing the liquid, the first and second compartments separated by a rupturable seal such that rupturing of the seal exposes the powder to the liquid.

6. The pharmaceutical formulation delivery system of claim 1, wherein at least one pharmaceutical formulation of the plurality of pharmaceutical formulations is in powder form and is prepackaged in a sufficient amount to provide dosing for seven days, the at least one pharmaceutical formulation prepackaged in a blister pack including a plurality of deformable blisters therein, each deformable blister containing one day'"'"'s dose of the at least one pharmaceutical formulation.

7. The pharmaceutical formulation delivery system of claim 1, wherein at least one pharmaceutical formulation of the plurality of pharmaceutical formulations is in powder form and comprises at least three pharmacologically active ingredients, the at least one prepackaged pharmaceutical formulation prepackaged in a blister pack including a plurality of deformable blisters therein, each deformable blister containing one pharmacologically active ingredient.

8. The pharmaceutical formulation delivery system of claim 1, wherein at least one pharmaceutical formulation of the plurality of prepackaged pharmaceutical formulations comprises a powder and a liquid and is prepackaged in a plastic receptacle, the plastic receptacle comprising a twist-off cap, at least a first and a second compartment for containing the powder, and a third compartment for containing the liquid, the at least first and second compartments separated from the third compartment by rupturable seals such that rupturing of the seals exposes the powder to the liquid.

9. A method of treating a patient having a particular condition, the method comprising the steps of:

a) evaluating the patient and determining a set of patient characteristics relating to the condition;

b) selecting a prepackaged pharmaceutical formulation from a chart listing a plurality of sets of patient characteristics relating to the condition and a plurality of prepackaged pharmaceutical formulations, each pharmaceutical formulation comprising at least two pharmacologically active ingredients in periodic dosage amounts for treating the condition, the chart indicating which of the plurality of pharmaceutical formulations is suitable for treating the patient; and

c) administering the prepackaged pharmaceutical formulation to the patient.

10. The method of claim 9, wherein the condition is selected from the group consisting of:

HIV/AIDS, cancer, heart failure, and coronary artery disease.