Ophthalmology implants and methods of manufacture
First Claim
Patent Images
1. An implant for treating glaucoma comprising:
- an inlet portion having an inlet lumen extending therethrough, the inlet lumen being in fluid communication with the anterior chamber of an eye when the implant is positioned within the trabecular meshwork of the eye; and
an outlet portion having an outlet lumen extending therethrough, the outlet lumen being in fluid communication with the inlet lumen and with an aqueous outflow channel of the eye when the outlet portion is disposed within the aqueous outflow channel of the eye and thereby permitting the transfer of fluid from the anterior chamber into the aqueous outflow channel;
wherein at least a portion of the implant comprises a nanostructure; and
wherein the aqueous outflow channel comprises at least one of Schlemm'"'"'s canal, a collector channel, and an episcleral vein.
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Abstract
The present disclosure provides an ophthalmology implant and methods for treating glaucoma or optic neural transmission deficiency, wherein at least a portion of the implant is made of or includes a nanometer-sized substance, such as nanotubes, nanofibers, sheets from nanotubes, nanowires, nanofibrous mesh and the like.
264 Citations
29 Claims
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1. An implant for treating glaucoma comprising:
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an inlet portion having an inlet lumen extending therethrough, the inlet lumen being in fluid communication with the anterior chamber of an eye when the implant is positioned within the trabecular meshwork of the eye; and
an outlet portion having an outlet lumen extending therethrough, the outlet lumen being in fluid communication with the inlet lumen and with an aqueous outflow channel of the eye when the outlet portion is disposed within the aqueous outflow channel of the eye and thereby permitting the transfer of fluid from the anterior chamber into the aqueous outflow channel;
wherein at least a portion of the implant comprises a nanostructure; and
wherein the aqueous outflow channel comprises at least one of Schlemm'"'"'s canal, a collector channel, and an episcleral vein. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. An implant for treating glaucoma comprising:
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an inlet portion having an inlet that is configured to receive fluid from the anterior chamber of an eye when the implant is positioned within the trabecular meshwork of the eye;
an outlet portion having an outlet that is configured to conduct fluid from the anterior chamber into at least one of Schlemm'"'"'s canal, a collector channel, and an episcleral vein of the eye when the outlet portion is positioned within the eye, thereby permitting the transfer of fluid from the anterior chamber into that at least one of Schlemm'"'"'s canal, a collector channel, and an episcleral veins; and
a layer of nanotubes disposed in or on the implant. - View Dependent Claims (23, 24, 25, 26, 27, 28)
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29. The implant of 22, wherein the implant further comprises an anchor that substantially prevents expulsion of the implant from the eye.
Specification