Fluid pressure actuated blood pumping systems and methods with continuous inflow and pulsatile outflow conditions

• US 20060178611A9
• Filed: 04/20/2004
• Published: 08/10/2006
• Est. Priority Date: 09/03/1999
• Status: Abandoned Application

• Current Assignee: Fenwal Incorporated (Fresenius SE & Co. KGaA)
• Original Assignee: Baxter International Inc.
• Inventors: Vandlik, Mark R., Westberg, Tom, Vishnoi, Rohit
• Application Number:
  US10/828,359
• Publication Number:
  US 20050234384A1
• Time in Patent Office: Days
• US Class Current: 604/6.30
• CPC Class Codes: A61M 1/30 Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/302 having a reservoir for withdrawn untreated blood
• CPC Class Codes: A61M 1/303 having a reservoir for treated blood to be returned
• CPC Class Codes: A61M 1/308 Volume control, e.g. with open or flexible containers, by counting the number of pump revolutions, weighing
• CPC Class Codes: A61M 1/36222 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/362261 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362262 Details of incorporated reservoirs
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/362266 Means for adding solutions or substances to the blood
• CPC Class Codes: A61M 1/3633 Blood component filters, e.g. leukocyte filters
• CPC Class Codes: A61M 1/3696 with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
• CPC Class Codes: A61M 2205/128 with incorporated valves
• CPC Class Codes: A61M 2205/331 used as turbidity change detectors, e.g. for priming-blood or plasma-hemoglubine-interface detection
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3393 by weighing the reservoir
• CPC Class Codes: A61M 60/109 incorporated within extracorporeal blood circuits or systems
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/36 for specific blood treatment; for specific therapy
• CPC Class Codes: A61M 60/427 the force acting on the blood contacting member being hydraulic or pneumatic
• CPC Class Codes: A61M 60/43 using vacuum at the blood pump, e.g. to accelerate filling
• CPC Class Codes: A61M 60/546 : of blood flow, e.g. by adapting rotor speed
• CPC Class Codes: A61M 60/847 : arranged in a cassette
• CPC Class Codes: A61M 60/892 : Active valves, i.e. actuated by an external force
• CPC Class Codes: A61M 60/894 : Passive valves, i.e. valves actuated by the blood
• CPC Class Codes: F04B 13/02 : of two or more fluids at the same time
• CPC Class Codes: F04B 2205/09 : Flow through the pump
• CPC Class Codes: F04B 43/026 : each plate-like pumping flexible member working in its own pumping chamber
• CPC Class Codes: F04B 49/065 : and making use of computers

Abstract

Blood processing systems and related methods place first and second fluid pressure actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. In the first flow mode, the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The systems and methods synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the destination is pulsatile.

Claims

1. A blood processing system comprising

a filter for removing leukocytes from blood,

first and second fluid pressure actuated pump stations, and

a fluid pressure actuator operating to selectively apply fluid pressure pump strokes in tandem to the first and second pump stations to convey fluid from a source to the filter, the fluid pressure actuator including a control function to switch between a first flow mode, in which the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the filter, and a second flow mode, in which the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the filter, the control function operating to synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the filter is pulsatile.

2. A system according to claim 1

wherein the source comprises a blood collection container.

3. A system according to claim 2

wherein the blood collection container receives blood from a blood separation device.

4. A system according to claim 1

wherein the first and second fluid pressure actuated pump stations apply positive and negative fluid pressure.

5. A system according to claim 1

wherein the first and second fluid pressure actuated pump stations apply positive and negative pneumatic pressure.

6. A system according to claim 1

wherein the filter communicates with a blood collection container located in a downstream flow direction to receive blood after passage through the filter.