Tissue penetration device

• US 20060178688A1
• Filed: 12/22/2005
• Published: 08/10/2006
• Est. Priority Date: 06/12/2001
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Boecker, Dirk, Alden, Don, Freeman, Dominique, Freeman, Ray, Briggs, Barry Dean, Gogue, George, Leonard, Jon Hewitt
• Granted Patent: US 8,211,037 B2
• Time in Patent Office: Days
• US Class Current: 606/181
• CPC Class Codes: A61B 17/32093 for skin incisions
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150061 Means for enhancing collection
• CPC Class Codes: A61B 5/150068 by tissue compression, e.g. with specially designed surface of device contacting the skin area to be pierced
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150152 by an adequate mechanical impact on the puncturing location
• CPC Class Codes: A61B 5/150167 Adjustable piercing speed of skin piercing element, e.g. blade, needle, lancet or canula, for example with varying spring force or pneumatic drive
• CPC Class Codes: A61B 5/150175 Adjustment of penetration depth
• CPC Class Codes: A61B 5/15019 Depth adjustment mechanism using movable stops located inside the piercing device housing and limiting the travel of the drive mechanism mechanisms using distal end caps A61B5/150183, mechanisms at the piercing element carrier proximal end A61B5/150198
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150221 Valves
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150427 Specific tip design, e.g. for improved penetration characteristics
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/150572 Pierceable protectors, e.g. shields, caps, sleeves or films, e.g. for hygienic purposes
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/15123 comprising magnets or solenoids
• CPC Class Codes: A61B 5/15146 Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means. multiple simultaneous cutting or piercing A61B5/150977
• CPC Class Codes: A61B 5/15151 : Each piercing element being stocked in a separate isolated compartment
• CPC Class Codes: A61B 5/15153 : Multiple piercing elements stocked in a single compartment
• CPC Class Codes: A61B 5/15163 : Characterized by propelling the piercing element in an axial direction relative to the disc
• CPC Class Codes: A61B 5/15169 : Characterized by a rolled strip
• CPC Class Codes: A61B 5/15171 : Characterized by propelling the piercing element perpendicular to the direction of movement of the strip
• CPC Class Codes: A61B 5/15176 : Stocking means comprising cap, cover, sheath or protection for aseptic stocking
• CPC Class Codes: A61B 5/15178 : Stocking means comprising separate compartments or units for new and for used piercing elements separate compartments for used piercing elements in piercing devices A61B5/15184
• CPC Class Codes: A61B 5/15184 : Piercing device comprising a separate compartment or unit for used piercing elements separate compartments for used piercing elements in stocking means A61B5/15178
• CPC Class Codes: A61B 5/15186 : Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
• CPC Class Codes: A61B 5/157 : Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61M 2005/004 : Magazines with multiple needles directly inserted into an injection or infusion device, e.g. revolver-like magazines
• CPC Class Codes: A61M 5/158 : Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
• CPC Class Codes: A61M 5/46 : having means for controlling depth of insertion
• CPC Class Codes: B01L 2200/10 : Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
• CPC Class Codes: B01L 2300/0663 : Whole sensors
• CPC Class Codes: B01L 2300/18 : Means for temperature control
• CPC Class Codes: B01L 3/5027 : by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip B01L3/5023 takes precedence; micromixers B01F33/30; microreactors for synthesis B01J19/0093; microcapillary devices in general B81B1/00
• CPC Class Codes: B01L 3/502715 : characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
• CPC Class Codes: B01L 3/50273 : characterised by the means or forces applied to move the fluids micropumps F04B19/006, of the membrane type F04B43/043
• CPC Class Codes: B01L 3/502746 : characterised by the means for controlling flow resistance, e.g. flow controllers, baffles B01L3/502738 takes precedence
• CPC Class Codes: G01N 33/4905 : Determining clotting time of blood by chemical methods G01N33/86, C12Q1/54
• CPC Class Codes: G01N 33/557 : using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction

Abstract

A system is provided that controls movement of a lancet. One or more processors execute program instructions and receive a data set. The program instructions are executed to cause the processor to, cause force to be applied to the lancet to thereby cause the lancet to move in a first direction toward a target, monitor position and speed of the lancet as the lancet moves in the first direction, adjust the application of force to the lancet as the lancet moves in the first direction to achieve a desired speed of the lancet, and adjust the application of force to the lancet when the lancet contacts the target so that the lancet penetrates the target within a desired range of speed.

Claims

1. A system that controls movement of a lancet, comprising one or more processors that execute program instructions and receive a data set, wherein the program instructions are executed to cause the processor to:

cause force to be applied to the lancet to thereby cause the lancet to move in a first direction toward a target;

monitor position and speed of the lancet as the lancet moves in the first direction;

adjust the application of force to the lancet as the lancet moves in the first direction to achieve a desired speed of the lancet;

adjust the application of force to the lancet when the lancet contacts the target so that the lancet penetrates the target within a desired range of speed.

2. A system as defined in claim 1, wherein the program instructions are executed to further cause the processor to cause force to be applied to the lancet by causing an electric current to be applied to a first coil to thereby create a magnetic field so that the first coil magnetically attracts the magnetic member.

3. A method as defined in claim 1, wherein the program instructions are executed to further cause the processor to cause force to be applied to the lancet to thereby cause the lancet to move in a second direction away from the target.

4. A program product for use in a processor that executes program steps recorded in a computer-readable media to perform a method for controlling movement of a lancet, the program product comprising:

a recordable media;

a program of computer-readable instructions executable by the processor to perform operations comprising;

causing force to be applied the lancet to thereby cause the lancet to move in a first direction toward a target;

monitoring position and speed of the lancet as the lancet moves in the first direction;

adjusting the application of force to the lancet as the lancet moves in the first direction to achieve a desired speed of the lancet;

adjusting the application of force to the lancet when the lancet contacts the target so that the lancet penetrates the target within a desired range of speed.

5. A system that controls movement of a lancet, the system comprising

one or more processors that execute program instructions and

receive a data set, wherein the program instructions cause the system to perform operations including:

applying a launching force to the lancet so that the lancet moves in a first direction toward a skin target;

controlling the application of the launching force to the lancet to thereby control the movement of the lancet as it moves in the first direction toward the skin target; and

applying a withdraw force to the lancet so that the lancet moves in a second direction away from the target.

6. A system as defined in claim 5, wherein applying a launching force to the lancet comprises energizing a coil to create a magnetic field that attracts a magnetic member disposed on the lancet to thereby cause the lancet to move in the first direction toward the skin target.

7. A system as defined in claim 5, wherein applying a withdraw force to the lancet comprises energizing a coil to create a magnetic field that attracts the magnetic member disposed on the lancet to thereby cause the lancet to move in the second direction away from the target.

8. A system as defined in claim 5, wherein the program instructions cause the system to perform operations further including:

applying a braking force to the lancet to decelerate the lancet as the lancet moves in the first direction toward the skin target such that a cutting tip of the lancet penetrates the skin target to a desired depth.

9. A system as defined in claim 5, wherein the program instructions cause the system to perform operations further including:

monitoring the position and speed of the lancet as the lancet moves in the first direction toward the skin target, wherein the application of the launching force to the lancet is controlled based on the position and speed of the lancet.

10. A system as defined in claim 5, wherein the withdraw force is applied to the lancet prior to the lancet contacting the skin target.

11. A system as defined in claim 5, wherein the program instructions cause the system to perform operations further including:

controlling the application of the launching force and the withdraw force so that the lancet moves toward the skin target at a maximum speed that is greater than a maximum speed at which the lancet moves away from the skin target.