Macroporous materials for use in aneurysms

• US 20060178696A1
• Filed: 02/04/2005
• Published: 08/10/2006
• Est. Priority Date: 02/04/2005
• Status: Abandoned Application

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Inventors: Carr-Brendel, Victoria E., Porter, Stephen Christopher
• Application Number:
  US11/051,578
• Publication Number:
  US 20060178696A1
• Time in Patent Office: Days
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12 for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord specially adapted for vas deferens or fallopian tubes A61F6/20; materials for ligaturing blood vessels A61L17/00
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12181 formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable, resorptive for implantable prostheses A61F2210/0004
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00898 expandable upon contact with fluid
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61L 2430/36 for embolization or occlusion, e.g. vaso-occlusive compositions or devices artificial blood vessels A61L27/507
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: A61L 31/146 Porous materials, e.g. foams or sponges

Abstract

This is a device for occluding a space within the body. In particular, the device comprises a porous material having a pore size of greater than about 30 microns and in which most of the pores of the porous material are co-continuous. The devices may be placed in a desired site within a mammal and are useful in inhibiting the formation of scar tissue.

Claims

1. A vaso-occlusive device comprising a macroporous material having a nominal pore size greater than about 30 microns, wherein at least 50 percent of the pores are interconnected with an adjacent pore.

2. The device of claim 1, wherein the pore size is between about 40 microns and about 400 microns.

3. The device of claim 1, wherein at least 80% of the pores are interconnected with an adjacent pore.

4. The device of claim 1, wherein the macroporous material comprises a polymer.

5. The device of claim 4, wherein the polymer is selected from the group consisting of silicones, polytetrafluoroethylene, polyesters, polyurethanes, proteins, hydrogel materials and combinations thereof.

6. The device of claim 1, further comprising a radioopaque material.

7. The device of claim 1, further comprising a structural element.

8. The device of claim 7, wherein the macroporous material at least partially surrounds, or is at least partially surrounded by, the structural element

9. The device of claim 8, wherein the macroporous material at least partially surrounds the structural element.

10. The device of claim 8, wherein the structural element at least partially surrounds the macroporous material.

11. The device of claim 7, comprising first and structural elements, wherein the macroporous material at least partially surrounds the first structural element and the second structural element at least partially surrounds the macroporous material.

12. The device of claim 7, wherein the macroporous material is attached to the structural element at one or more locations.

13. The device of claim 7, wherein the structural element comprises a metal.

14. The device of claim 13, wherein the metal is selected from the group consisting of nickel, titanium, platinum, gold, tungsten, iridium and alloys or combinations thereof.

15. The device of claim 14, wherein the metal is nitinol or platinum.

16. The device of claim 7, wherein the structural element comprises a coil, the coil comprising a metal selected from the group consisting of platinum, palladium, rhodium, gold, tungsten and alloys thereof.

17. The device of claim 7, wherein the structural element comprises a coil, the coil comprising a stainless steel or super-elastic metal alloy.

18. The device of claim 7, wherein the structural element comprises a tubular braid.

19. The device of claim 7, wherein the structural element comprises a biodegradable material.

20. The device of claim 7, wherein the structural element further comprises a detachment junction.

21. The device of claim 20, wherein the detachment junction comprises an electrolytically detachable end adapted to detach from a pusher by imposition of a current on the pusher.

22. The device of claim 1, further comprising bioactive component.

23. The device of claim 7, further comprising bioactive component.

24. A method of occluding a body cavity comprising introducing a vaso-occlusive device according to claim 1 into the body cavity.

25. The method of claim 23, wherein the body cavity is an aneurysm.