Composition for gelatin coating, gelatin coating, and preparation using the same

• US 20060182798A1
• Filed: 01/26/2006
• Published: 08/17/2006
• Est. Priority Date: 07/30/2004
• Status: Abandoned Application

• Current Assignee: Wakunaga Pharmaceutical Co., Ltd.
• Original Assignee: Wakunaga Pharmaceutical Co., Ltd.
• Inventors: Shimokawa, Yoshiyuki, Shiraishi, Sumihiro, Mihara, Mika
• Application Number:
  US11/342,324
• Publication Number:
  US 20060182798A1
• Time in Patent Office: Days
• US Class Current: 424/456
• CPC Class Codes: A61K 9/2873 Proteins, e.g. gelatin
• CPC Class Codes: A61K 9/4825 Proteins, e.g. gelatin gelatin capsule shells with substantial amounts of other macromolecular substances A61K9/4816
• CPC Class Codes: A61P 3/00 Drugs for disorders of the metabolism of the blood or the extracellular fluid A61P7/00

Abstract

The present invention relates to a composition for gelatin coating and a gelatin coating characterized by containing a gelatin (A) and an inositol phosphate (B) represented by a general formula: C₆H_12-n.(H₂PO₄)_n (in the formula, n represents an integer from 1 to 6), and a preparation using the same.

Claims

1. A composition for a gelatin coating characterized by comprising a gelatin (A) and an inositol phosphate (B) represented by a general formula:

C₆H_12-n.(H₂PO₄)_n (wherein n represents an integer from 1 to

     6).

2. A gelatin coating characterized by comprising a gelatin (A) and an inositol phosphate (B) represented by a general formula:

C₆H_12-n.(H₂PO₄)_n (wherein n represents an integer from 1 to

     6).

3. A gelatin coating according to claim 2, characterized in that the component (B) comprises an inositol hexaphosphate.

4. A preparation characterized by comprising a gelatin coating according to claim 2.

5. A preparation according to claim 4, characterized in that a filled content thereof comprises at least one selected from the group consisting of galenicals, unsaturated fatty acids, unsaturated fatty acid residue-containing oils and fats, minerals, mineral-containing yeasts, and a vitamin C.

6. A preparation according to claim 4, characterized in that a filled content thereof comprises at least one selected from the group consisting of phospholipids, amino sugars, and organic acids.

7. A preparation according to claim 4, characterized by being any one selected from a capsule, a sugar-coated tablet, and a glue-coated tablet.

8. A preparation according to claim 4, characterized by being a soft capsule.

9. A production method of the preparation according to claim 8, characterized by comprising a production step of a composition for a gelatin coating containing at least a gelatin (A) and an inositol phosphate (B) represented by a general formula:

C₆H_12-n.(H₂PO₄)_n (wherein n represents an integer from 1 to

     6) and an encapsulation step in which the gelatin coating is produced from the composition for the gelatin coating and a content to be filled in the preparation is interposed between the gelatin coating followed by a pressure bonding.

10. A production method according to claim 9, characterized by further comprising a step of preparing the content to be filled containing at least one selected from the group consisting of phospholipids, amino sugars, and organic acids.

11. A method for preventing insolubilization of a gelating coating, characterized by comprising formulating an inositol phosphate (B) represented by a general formula:

C₆H_12-n.(H₂PO₄)_n (wherein n represents an integer from 1 to

     6) into a gelatin.