Methods and apparatus for extracting and analyzing a component of a bodily fluid
First Claim
1. A system for bodily fluid sampling and analysis, said system comprising:
- a first fluid passageway having a patient end which is configured to provide fluid communication with a bodily fluid within a patient;
a sample analysis chamber accessible via said first fluid passageway;
at least one pump in operative engagement with said first fluid passageway such that said system is operable to periodically draw a sample of said bodily fluid from said patient through said first fluid passageway and toward said sample analysis chamber;
a separator accessible via said first fluid passageway and configured to remove at least one component from said sample of bodily fluid; and
a spectroscopic analyte detection system configured to analyze said component of bodily fluid while said component of bodily fluid is in said sample analysis chamber, and determine a concentration of at least one analyte.
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Accused Products
Abstract
In some embodiments, a system for bodily fluid sampling and analysis comprises a first fluid passageway having a patient end which is configured to provide fluid communication with a bodily fluid within a patient. A sample analysis chamber is accessible via the first fluid passageway. At least one pump is in operative engagement with the first fluid passageway such that the system is operable to periodically draw a sample of the bodily fluid from the patient through the first fluid passageway and toward the sample analysis chamber. A separator is accessible via the first fluid passageway and configured to remove at least one component from the sample of bodily fluid. A spectroscopic analyte detection system is configured to analyze the component of bodily fluid while the component of bodily fluid is in the sample analysis chamber, and determine a concentration of at least one analyte.
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Citations
61 Claims
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1. A system for bodily fluid sampling and analysis, said system comprising:
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a first fluid passageway having a patient end which is configured to provide fluid communication with a bodily fluid within a patient;
a sample analysis chamber accessible via said first fluid passageway;
at least one pump in operative engagement with said first fluid passageway such that said system is operable to periodically draw a sample of said bodily fluid from said patient through said first fluid passageway and toward said sample analysis chamber;
a separator accessible via said first fluid passageway and configured to remove at least one component from said sample of bodily fluid; and
a spectroscopic analyte detection system configured to analyze said component of bodily fluid while said component of bodily fluid is in said sample analysis chamber, and determine a concentration of at least one analyte. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A system for periodically drawing a blood sample from a patient and analyzing the composition of at least one component of said blood sample, said system comprising:
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a fluid passageway having a distal end which is configured to be inserted into the vasculature of a patient;
a sample analysis chamber in fluid communication with said fluid passageway;
an infusion fluid source in fluid communication with said fluid passageway, said source containing an infusion fluid;
a pump unit, said pump unit having a first mode in which said pump unit infuses said infusion fluid into said patient via said fluid passageway, and a second mode in which said pump unit is operable to draw a blood sample from said patient via said first fluid passageway and toward said sample analysis chamber;
a separator configured to remove at least one component from said blood sample before said sample is analyzed by said analyte detection system; and
a spectroscopic analyte detection system configured to analyze said at least one component while at least a portion of said at least one component is in said sample analysis chamber, and determine a concentration of at least one analyte. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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34. The system of 33, wherein said pump unit comprises a first pump operable in said first mode and a second pump operable in said second mode.
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35. A fluid handling and analysis system, said system comprising:
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a fluid handling network comprising at least one fluid passageway, said fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient;
a sample analysis chamber accessible via said fluid handling network;
a pump unit coupled to said fluid handling network, said pump unit having a sample draw mode in which said pump unit is operable to draw a sample of said bodily fluid from said patient through said patient end, toward said sample analysis chamber;
a spectroscopic fluid analyzer configured to analyze said sample of bodily fluid while said sample of bodily fluid is in said sample analysis chamber, and determine a concentration of at least one analyte; and
a separator configured to remove at least one component from said sample of bodily fluid before said sample is analyzed by said analyte detection system. - View Dependent Claims (36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52)
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53. A method of extracting and analyzing a bodily fluid of a patient, said method comprising:
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establishing fluid communication between a fluid transport network and a bodily fluid of a patient, wherein said fluid transport network further comprises at least one fluid passageway and a fluid component separator;
drawing a volume of bodily fluid from said patient into said fluid transport network;
transporting said volume of bodily fluid to said fluid component separator via said at least one fluid passageway;
with said fluid component separator, separating a first component from said bodily fluid;
transporting said first component to a sample analysis chamber, wherein said sample analysis chamber is operatively engaged with an analyte detection system; and
with said analyte detection system, analyzing said first component to measure the concentration of an analyte. - View Dependent Claims (54, 55, 56, 57, 58, 59, 60, 61)
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Specification