Intra-aortic renal drug delivery catheter
9 Assignments
0 Petitions
Accused Products
Abstract
A catheter for delivering a therapeutic or diagnostic agent to a branch blond vessel of a major blood vessel comprises an elongated shaft having at least one lumen in fluid communication with an agent delivery port in a distal section of the shaft, an expandable tubular member on the distal section of the shaft, and a radially expandable member on the tubular member. The tubular member is configured to extend within the blood vessel up-stream and down-stream of a branch vessel, and has an interior passageway which is radially expandable within the blood vessel to separate blood flow through the blood vessel into an outer blood flow stream exterior to the tubular member and an inner blood flow stream within the interior passageway of the tubular member.
239 Citations
36 Claims
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1-22. -22. (canceled)
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23. A method for enhancing renal function in a patient, comprising:
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diverting a portion of aortic blood flowing into a location within an abdominal aorta to flow along a diverted flow path substantially only into a plurality of renal arteries via a plurality of respective ostia having unique respective locations along the abdominal aorta wall;
injecting a volume of fluid agent into the diverted flow path within the abdominal aorta at the location;
wherein the injected fluid agent is delivered substantially only into the plurality of renal arteries via the diverted flow path into their respective ostia; and
wherein the fluid agent being delivered into the plurality of renal arteries is adapted to enhance renal function. - View Dependent Claims (24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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34. A system for enhancing renal function in a patient, comprising:
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a delivery catheter with a proximal end portion and a distal end portion with a fluid delivery port;
a flow diverter located along the distal end portion;
a source of fluid agent;
wherein the delivery catheter is adapted to couple to the source of fluid agent;
wherein the delivery catheter is adapted to position the distal end portion at a location within an abdominal aorta associated with a plurality of renal artery ostia having unique respective positions along the abdominal aorta wall;
wherein the flow diverter at the location is adapted to divert a portion of aortic blood flow along a diverted flow path substantially only into the plurality of renal arteries via their respective ostia;
wherein the fluid delivery port is positioned relative to the flow diverter so as to inject a volume of the fluid agent from the source into the diverted flow path; and
wherein the fluid agent is adapted to enhance renal function. - View Dependent Claims (35)
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36-49. -49. (canceled)
Specification