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Enhanced systems and methods for RF-induced hyperthermia

  • US 20060190063A1
  • Filed: 02/03/2005
  • Published: 08/24/2006
  • Est. Priority Date: 05/07/2004
  • Status: Active Grant
First Claim
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1. A method of inducing hyperthermia in at least target cells of a patient, comprising the steps of:

  • (a) providing an RF transmitter having an RF generator in circuit communication with a transmission head, the RF generator capable of generating a hyperthermia-inducing RF signal having at least the one frequency for transmission via the transmission head;

    (b) providing targeted RF absorption enhancers characterized by binding to the target cells to thereby increase heating of target cells responsive to the RF signal by interaction between the RF signal and the targeted RF absorption enhancer;

    (c) introducing the targeted RF absorption enhancers into the patient;

    (d) waiting for at least some of the targeted RF absorption enhancers to bind to some of the target cells;

    (e) arranging the transmission head proximate to at least one body part of the patient containing the target cells in such a manner that the RF signal transmitted via the transmission head passes through and warms at least the targeted RF absorption enhancers bound to target cells;

    (f) transmitting the RF signal via the transmission head, thereby warming the targeted RF absorption enhancers bound to target cells; and

    (g) receiving at least a portion of the RF signal that passed through the patient.

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