Methods and compositions for biocidal treatments

• US 20060193816A1
• Filed: 02/07/2006
• Published: 08/31/2006
• Est. Priority Date: 02/07/2005
• Status: Active Grant

• Current Assignee: Termpro LLC
• Original Assignee: Sishield Technologies, Inc.
• Inventors: Villahoz, Marcello D., Elfersy, Jacques
• Granted Patent: US 8,999,357 B2
• Time in Patent Office: Days
• US Class Current: 424/70.28
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 31/02 Acyclic compounds
• CPC Class Codes: A01N 33/12 Quaternary ammonium compounds
• CPC Class Codes: A01N 55/00 Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing organo-phosphorus compounds A01N57/00
• CPC Class Codes: A01N 59/00 Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• CPC Class Codes: A61K 8/416 Quaternary ammonium compounds A61K8/35 takes precedence
• CPC Class Codes: A61K 8/898 containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: D06M 11/50 with hydrogen peroxide or peroxides of metals; with persulfuric, permanganic, pernitric, percarbonic acids or their salts
• CPC Class Codes: D06M 13/342 Amino-carboxylic acids; Betaines; Aminosulfonic acids; Sulfo-betaines
• CPC Class Codes: D06M 13/463 derived from monoamines
• CPC Class Codes: D06M 13/513 with at least one carbon-silicon bond
• CPC Class Codes: D06M 16/00 Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic

Abstract

The present invention provides a composition having disinfectancy & residual antimicrobial activity, where the antimicrobial composition comprises an organosilane quaternary compound and a quaternary ammonium compound and other formulations. Also provided are methods of disinfecting an article or providing an antimicrobial coating to an article using the same.

Claims

1. A method of disinfecting an article comprising contacting the article with an aqueous composition having antimicrobial activity, wherein the aqueous composition comprises an organosilane quaternary compound and a quaternary ammonium compound, and wherein the quaternary ammonium compound is not an organosilane quaternary compound.

2. The method of claim 1, wherein the organosilane quaternary compound is a compound having formula R_nSiX_(4-n), wherein (1) R is, independently, an alkene group, an alkyl group, or an alkyne group, and (2) X is, independently, an alkoxy group;

and wherein each of the alkene group, the alkyl group, the alkyne group, and the alkoxy group optionally comprises an amino, a chloro, an epoxy, or a mercapto substituent.

3. The method of claim 2, wherein the organosilane quaternary compound is selected from the group consisting of 3-trimethoxysilyl propyltetradecyldimethyl ammonium chloride, 3-trimethoxysilyl propyldidecylmethyl ammonium chloride, and 3-trihydroxysilyl propyloctadecyl ammonium chloride.

4. The method of claim 1, wherein the quaternary ammonium compound comprises at least one compound selected from the group consisting of mono-long-chain, tri-short-chain, tetraalkyl ammonium compounds;

di-long-chain, di-short-chain, tetraalkyl ammonium compounds; and

trialkyl, mono-benzyl ammonium compounds.

5. The method of claim 1, wherein the quaternary ammonium compound comprises at least one of chloride or saccharinate counterion.

6. The method of claim 1, comprising a ratio of organosilane quaternary compound to quaternary ammonium compound in a weight range of about 1:

100 to about 100;

1.

7. The method of claim 1, wherein the aqueous composition further comprises at least one agent selected from the group consisting of an oxidizing agent, a chelating agent, and a stabilizing agent.

8. The method of claim 7, wherein the aqueous composition further comprises at least one agent selected from the group consisting of hydrogen peroxide, ethylenediaminetetraacetic acid (EDTA) and a salt thereof, propelyne carbonate, Glycol Ether, a polyol, and sucrose.

9. A method of providing an antimicrobial or disinfectant coating to an article comprising contacting the article with an aqueous composition having antimicrobial activity, wherein the aqueous composition comprises an organosilane quaternary compound and a quaternary ammonium compound, and wherein the quaternary ammonium compound is not an organosilane quaternary compound.

10. The method of claim 9, wherein the organosilane quaternary compound is a compound having formula R_nSiX_(4-n), wherein (1) R is, independently, an alkene group, an alkyl group, or an alkyne group, and (2) X is, independently, an alkoxy group;

and wherein each of the alkene group, the alkyl group, the alkyne group, and the alkoxy group optionally comprises an amino, a chloro, an epoxy, or a mercapto substituent.

11. The method of claim 10, wherein the organosilane quaternary compound is selected from the group consisting of 3-trimethoxysilyl propyltetradecyldimethyl ammonium chloride, 3-trimethoxysilyl propyldidecylmethyl ammonium chloride, and 3-trihydroxysilyl propyloctadecyl ammonium chloride.

12. The method of claim 9, wherein the quaternary ammonium compound comprises at least one compound selected from the group consisting of mono-long-chain, tri-short-chain, tetraalkyl ammonium compounds;

di-long-chain, di-short-chain, tetraalkyl ammonium compounds; and

trialkyl, mono-benzyl ammonium compounds.

13. The method of claim 9, wherein the quaternary ammonium compound comprises at least one of chloride or saccharinate counterion.

14. The method of claim 9, comprising a ratio of organosilane quaternary compound to quaternary ammonium compound in a weight range of about 1:

100 to about 100;

1.

15. The method of claim 9, wherein the aqueous composition further comprises at least one agent selected from the group consisting of an oxidizing agent, a chelating agent, and a stabilizing agent.

16. The method of claim 15, wherein the aqueous composition further comprises at least one agent selected from the group consisting of hydrogen peroxide, ethylenediaminetetraacetic acid (EDTA) and a salt thereof, propelyne carbonate, Glycol Ether, a polyol, and sucrose.

17. An aqueous composition having antimicrobial activity comprising an organosilane quaternary compound and a quaternary ammonium compound, wherein the quaternary ammonium compound is not an organosilane quaternary compound.

18. The aqueous composition of claim 17, wherein the organosilane quaternary compound is a compound having formula R_nSiX_(4-n), wherein (1) R is, independently, an alkene group, an alkyl group, or an alkyne group, and (2) X is, independently, an alkoxy group;

and wherein each of the alkene group, the alkyl group, the alkyne group, and the alkoxy group optionally comprises an amino, a chloro, an epoxy, or a mercapto substituent.

19. The aqueous composition of claim 17, wherein the quaternary ammonium compound comprises at least one compound selected from the group consisting of mono-long-chain, tri-short-chain, tetraalkyl ammonium compounds;

di-long-chain, di-short-chain, tetraalkyl ammonium compounds; and

trialkyl, mono-benzyl ammonium compounds.

20. The aqueous composition of claim 17, wherein the aqueous composition further comprises at least one agent selected from the group consisting of an oxidizing agent, a chelating agent, and a stabilizing agent.