Analyte detection system with reduced sample volume
First Claim
1. A method of sampling a body fluid of a patient, said method comprising:
- providing a fluid handling system having one or more fluid passageways;
with said fluid handling system, infusing an infusion fluid into said patient through said one or more fluid passageways;
with said fluid handling system, obtaining a sample of said body fluid from said patient through said one or more fluid passageways, said obtained sample being no more than 400 microliters in volume; and
with an analyte detection system operatively associated with said fluid handling system, analyzing at least an analyzed portion of said obtained sample to determine a concentration of at least one analyte.
6 Assignments
0 Petitions
Accused Products
Abstract
In certain embodiments, a method samples a body fluid of a patient. The method includes providing a fluid handling system having one or more fluid passageways. The method further includes infusing an infusion fluid by way of a fluid handling system into a patient through one or more fluid passageways. The method further includes obtaining a sample of body fluid by way of a fluid handling system from a patient through one or more fluid passageways. The obtained sample is no more than 400 microliters in volume. The method further includes analyzing at least an analyzed portion of the obtained sample by way of an analyte detection system operatively associated with the fluid handling system to determine a concentration of at least one analyte.
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Citations
72 Claims
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1. A method of sampling a body fluid of a patient, said method comprising:
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providing a fluid handling system having one or more fluid passageways;
with said fluid handling system, infusing an infusion fluid into said patient through said one or more fluid passageways;
with said fluid handling system, obtaining a sample of said body fluid from said patient through said one or more fluid passageways, said obtained sample being no more than 400 microliters in volume; and
with an analyte detection system operatively associated with said fluid handling system, analyzing at least an analyzed portion of said obtained sample to determine a concentration of at least one analyte. - View Dependent Claims (2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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8. The method of Claim I, wherein said analyte is lactate.
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21. A body fluid handling system comprising:
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a fluid handling network having a patient end, said fluid handling network configured to provide access to a body fluid in a patient;
a pump system coupled to said fluid handling network, said pump system having a first mode in which said pump system is operable to infuse an infusion fluid toward said patient via said fluid handling network and a second mode in which said pump system is operable to draw a sample of said body fluid from said patient into said fluid handling network;
an analyte detection system accessible via said fluid handling network and configured to measure an analyte in at least a portion of said drawn sample of body fluid;
said fluid handling network having a maximum draw region associated with a maximum draw state of the fluid handling system; and
said maximum draw region having a volume of no more than 400 microliters. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
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41. A body fluid analysis system comprising:
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a fluid passageway;
an analyzer accessible via said fluid passageway and configured to provide information relating to a measurement of an analyte in a sample;
a processor in communication with said analyzer; and
stored program instructions executable by said processor such that said system, upon execution of said stored program instructions, is operable to;
(a) infuse an infusion fluid toward a patient end of the fluid passageway;
(b) draw said sample through said fluid passageway away from said patient end and toward said analyzer, said drawn sample being no more than 400 microliters in volume; and
(c) analyze at least a portion of said drawn sample to determine a concentration of at least one analyte. - View Dependent Claims (42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56)
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57. A fluid handling module usable with a body fluid analyzer having a pump system and an analyte detection system, said fluid handling module comprising:
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a fluid transport network having a patient end and an interface portion spaced from said patient end and configured to engage said pump system, said fluid transport network configured to obtain a body fluid from a patient;
a sample analysis cell accessible via said fluid transport network and configured to interface with said analyte detection system;
said fluid transport network having a maximum draw region associated with a maximum draw state of the network;
said maximum draw region having a volume of no more than 400 microliters. - View Dependent Claims (58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72)
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Specification