Electrode substrate, detection device equipped with electrode substrate, detection device kit and detection method using the kit

• US 20060196779A1
• Filed: 02/24/2006
• Published: 09/07/2006
• Est. Priority Date: 03/07/2005
• Status: Active Grant

• Current Assignee: Seiko Epson Corporation (Seiko Group)
• Original Assignee: Seiko Epson Corporation (Seiko Group)
• Inventors: Takiguchi, Hiroshi, Fukushima, Hitoshi
• Granted Patent: US 8,343,333 B2
• Time in Patent Office: Days
• US Class Current: 205/792
• CPC Class Codes: B82Y 15/00 Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• CPC Class Codes: B82Y 30/00 Nanotechnology for materials or surface science, e.g. nanocomposites
• CPC Class Codes: B82Y 40/00 Manufacture or treatment of nanostructures
• CPC Class Codes: C12Q 1/003 Functionalisation

Abstract

An electrode substrate including an electrode and a membrane provided on the electrode and having a thickness with which a carrier is exchanged between the electrode and the membrane.

Claims

1. An electrode substrate, comprising:

an electrode; and

a membrane provided on the electrode and having a thickness with which a carrier is exchanged between the electrode and the membrane.

2. The electrode substrate according to claim 1, wherein the thickness is 10-80 {acute over (Å

)}.

6. The electrode substrate according to claim 1, wherein the membrane is a monolayer including a chemical compound selected from the group consisting of a compound having a group represented by —

CH₂—

, a compound having a group represented by —

CH₂CH₂O—

, a compound having groups represented by —

CH₂— and

—

CH₂CH₂O— and

a compound having a group represented by the following formula (1) Formula (1)

7. The electrode substrate according to claim 1, wherein the membrane includes a functional group and a mediator or a biomolecule through the functional group.

8. The electrode substrate according to claim 1, wherein the electrode and the membrane are bonded through a sulfur atom or an oxygen atom.

9. The electrode substrate according to claim 7, wherein the biomolecule is selected from the group consisting of nucleic acid, protein, enzyme and antibody.

10. A detection device, comprising:

the electrode substrate according to claim 1;

a counter electrode opposing the electrode substrate; and

a reference electrode.

11. The detection device according to claim 10, further comprising:

a detection circuit individually coupled to the electrode substrate, the counter electrode and the reference electrode.

12. A detection kit for detecting a subject material, comprising:

the detection device according to claim 10;

and

a biomolecule or a mediator reacting with the subject material.

13. The detection kit according to claim 12, further comprising a buffer solution.

14. A method of detecting a subject material in a sample, comprising:

providing the detection kit according to claim 12;

and

contacting the sample with the kit.

15. The method of detecting a subject material in a sample according to claim 14, further comprising:

measuring a current value in the presence of the subject material.

3. An electrode substrate, comprising:

an electrode; and

a membrane made of a material that includes an oxygen atom and provided on the electrode.

4. The electrode substrate according to claim 3, wherein the membrane is made of the material that has the oxygen atom in its main chain.

5. The electrode substrate according to claim 3, wherein the material includes a chemical compound having a straight-chain structure and an oxygen atom in the straight-chain structure.