ON-CHIP SPECTRAL FILTERING USING CCD ARRAY FOR IMAGING AND SPECTROSCOPY

• US 20060197949A1
• Filed: 03/02/2005
• Published: 09/07/2006
• Est. Priority Date: 03/02/2005
• Status: Active Grant

• Current Assignee: Li-Cor Biotech LLC
• Original Assignee: Li & S Company Limited (Yesco Holdings Co., Ltd.)
• Inventors: BOUZID, Ahmed, FRANZEN, David L., LESIAK, Christopher
• Granted Patent: US 7,130,041 B2
• Time in Patent Office: Days
• US Class Current: 356/328
• CPC Class Codes: G01J 3/2803 using photoelectric array detector
• CPC Class Codes: G01J 3/4406 Fluorescence spectrometry

Abstract

A spectral filtering apparatus and method is presented, which enables the functions of hyperspectral imaging to be performed with increased speed, simplicity, and performance that are required for commercial products. The apparatus includes a photosensitive array having a plurality of photosensitive elements such that different subsections of photosensitive elements of the array receive light of a different wavelength range of a characteristic spectrum of a target, and output electronics combines signals of at least two photosensitive elements in a subsection of the array and outputs the combined signal as a measure of the optical energy within a bandwidth of interest of the characteristic spectrum.

Claims

1. A spectral filter, comprising:

a photosensitive array having a plurality of photosensitive elements, at least a subsection of photosensitive elements of said array along one direction thereof being configured such that each element of said subsection along said one direction receives light of a different wavelength range of a characteristic spectrum and produces an electrical signal corresponding thereto,

said subsection being configured to combine signals of at least two photosensitive elements and to output said combined signal as a measure of the optical energy within a bandwidth of interest of said characteristic spectrum.

2. The spectral filter of claim 1, wherein said array is a CCD array.

3. The spectral filter of claim 1, wherein said array is a CMOS array.

4. The spectral filter of claim 1, wherein said array is a PhotoDiode (PD) array.

5. The spectral filter of claim 1, wherein said array is an Avalanche PhotoDiode (APD) array.

6. The spectral filter of claim 1, wherein said array is a PMT array.

7. The spectral filter of claim 1, further comprising a dispersive element for spreading said characteristic spectrum across a dimension of said photosensitive array corresponding to said one direction.

8. The spectral filter of claim 7, wherein said photosensitive array is an area array, and said one direction corresponds to different lines of photosensitive elements.

9. The spectral filter of claim 7, wherein said photosensitive array is a line array, and said one direction corresponds to different photosensitive elements.

10. The spectral filter of claim 7, wherein said dispersive element is a transmission grating.

11. The spectral filter of claim 7, wherein said dispersive element is a prism.

12. A system for spectral imaging of a target, comprising:

a photosensitive array having a plurality of photosensitive elements;

an illumination source for excitation of said target;

imaging optics that focuses and spreads light emitted from said target in response to excitation from said illumination source over said photosensitive array, such that different subsections of photosensitive elements of said array receive light of a different wavelength range of a characteristic spectrum of said target; and

output electronics coupled to said photosensitive array and receiving electrical signals from said photosensitive elements, combining signals of at least two photosensitive elements in a subsection and outputting said combined signal as a measure of the optical energy within a bandwidth of interest of said characteristic spectrum.

13. The system of claim 12, wherein said array is a CCD array.

14. The system of claim 12, wherein said illumination source is a laser source.

15. The system of claim 14, wherein said laser source comprises a plurality of lasers, each producing light of a different wavelength.

16. The system of claim 12, wherein said imaging optics comprises a focusing lens and a dispersive element.

17. The system of claim 12, wherein said dispersive element is a transmission grating.

18. The system of claim 12, wherein said dispersive element is a prism.

19. The system of claim 12, wherein said output electronics is programmable to select different combinations of photosensitive elements for signal combination.

20. The system of claim 19, wherein said photosensitive array is an area array, and said output electronics is programmable to select different lines of photosensitive elements for signal combination.

21. The system of claim 19, wherein said photosensitive array is a line array, and said output electronics is programmable to select different photosensitive elements for signal combination.

22. A method of performing spectral filtering using a photosensitive array having a plurality of photosensitive elements, comprising the steps of:

calibrating said array such that each element of said photosensitive array along one direction thereof corresponds to a different wavelength range of a characteristic spectrum projected onto said array;

configuring a read-out process of said array to combine signals of at least two photosensitive elements along said one direction, generated in response to illumination by said characteristic spectrum, as a measure of the optical energy within a bandwidth of interest of said spectrum.

23. The method of claim 22, wherein said array is a CCD array.

24. The method of claim 22, wherein the step of calibrating comprises the step of positioning said array with respect to a target emitting said characteristic spectrum and with respect to imaging optics positioned between said array and said target.

25. The method of claim 22, wherein the step of configuring comprises the step of programming output electronics with respect to generation of timing signals applied to an output register coupled to receive signals from said photosensitive elements.

26. The method of claim 23 wherein said CCD array is an area array, and further comprising the step of using a zero order line of said array for focusing of said characteristic spectrum.