Biocompatible implant device
First Claim
1. A medical implant made of an elastic, solid, biocompatible, and non-hemolytic device having a thickness of less than about 5 mm, a modulus of elasticity between about 10 kPa and about 100 MPa, and a pore size of less than about 10 microns that prevents growth and passage of cells through the implant device, while allowing water and nutrient transport across the implant device.
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Abstract
A medical implant made of an elastic, solid, biocompatible, and non-hemolytic material having a thickness of less than about 5 mm, a modulus of elasticity between about 10 kPa and about 100 MPa. The implant device has a pore size of less than about 10 microns in order to prevent growth and passage of cells through the implant, while allowing water and nutrient transport across the implant device.
43 Citations
12 Claims
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1. A medical implant made of an elastic, solid, biocompatible, and non-hemolytic device having a
thickness of less than about 5 mm, a modulus of elasticity between about 10 kPa and about 100 MPa, and a pore size of less than about 10 microns that prevents growth and passage of cells through the implant device, while allowing water and nutrient transport across the implant device.
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11. A medical implant made of an elastic, solid, biocompatible, and non-hemolytic synthetic organic polymer device having a tubular shape,
a uniform thickness of less than about 5 mm, a modulus of elasticity between about 10 kPa and about 100 MPa, an ultimate stretch of greater than 200 percent, and a pore size of less than about 10 microns that prevents growth and passage of cells through the surfaces of the device, while allowing anisotropic water and nutrient transport across the surfaces and ends of the device.
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12. A method of making a semi-crystalline, solid, biocompatible and non-hemolytic implant device having a thickness of less than about 5 mm comprising:
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mixing a solution of water and polyvinyl alcohol thereby forming an aqueous PVA mixture;
inserting a solid mandrel into said aqueous PVA mixture whereby the viscosity of said aqueous PVA mixture causes said aqueous PVA mixture to adhere to said mandrel;
spinning said mandrel within a non-aqueous environment or air in order to allow said aqueous PVA mixture to solidify at a uniform thickness about said mandrel;
freezing and thawing said aqueous PVA mixture at least once in order to create a semi-crystalline solid biocompatible implant device; and
removing said mandrel from said semi-crystalline solid biocompatible implant device.
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Specification