Flexible markers

• US 20060201601A1
• Filed: 01/04/2006
• Published: 09/14/2006
• Est. Priority Date: 03/03/2005
• Status: Abandoned Application

• Current Assignee: ICON Interventional Systems, Inc.
• Original Assignee: ICON Interventional Systems, Inc.
• Inventors: Furst, Joseph G., Brodbeck, William, Wiggins, Michael J.
• Application Number:
  US11/325,476
• Publication Number:
  US 20060201601A1
• Time in Patent Office: Days
• US Class Current: 156/60
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers
• CPC Class Codes: A61M 25/0108 using radio-opaque or ultrasound markers
• CPC Class Codes: Y10T 156/10 Methods of surface bonding and/or assembly therefor

Abstract

A flexible marker material that is visible to at least one form of electromagnetic wave, sound wave and/or magnetic wave. The marker material is used on a medical device and adds little or no bulk to the medical device.

Claims

1. A medical device that includes a body portion having at least one marker material, said marker material visible to at least one form of electromagnetic wave, sound wave, magnetic wave or combinations thereof, said marker material formed of a flexible and non-rigid material, said marker material including adhesive material, metal powder and protective material.

2. The medical device as defined in claim 1, wherein said medical device is at least partially coated with said marker material.

3. The medical device as defined in claim 1, wherein said adhesive material includes a silicone adhesive, a silicone based adhesive, a polyurethane adhesive, a polyurethane based adhesive, an acrylic adhesive, an acrylic based adhesive, or combinations thereof.

4. The medical device as defined in claim 1, where in said adhesive layer has an average thickness of about 2-50 microns.

5. The medical device as defined in claim 3, where in said adhesive layer has an average thickness of about 2-50 microns.

6. The medical device as defined in claim 1, wherein a majority weight percent of said metal powder includes bismuth, molybdenum, rhenium, tungsten, or combinations thereof.

7. The medical device as defined in claim 5, wherein a majority weight percent of said metal powder includes bismuth, molybdenum, rhenium, tungsten, or combinations thereof.

8. The medical device as defined in claim 1, wherein at least about 95 percent of said metal powder has an average particle size of about 5-150 microns.

9. The medical device as defined in claim 7, wherein at least about 95 percent of said metal powder has an average particle size of about 5-150 microns.

10. The medical device as defined in claim 1, wherein a majority of said metal powder is in the form of a metal layer that is positioned on a layer of said adhesive material.

11. The medical device as defined in claim 1, wherein a majority of said metal powder is radiopaque.

12. The medical device as defined in claim 1, wherein said protective material covers at least about 95 percent of said metal powder.

13. The medical device as defined in claim 1, wherein said protective material has a coating thickness of about 0.1-10 microns.

14. The medical device as defined in claim 10, wherein said protective material has a coating thickness of about 0.1-10 microns.

15. The medical device as defined in claim 1, wherein said protective material includes at least one polymer, said at least one polymer including parylene, parylene derivatives or combinations thereof

16. The medical device as defined in claim 14, wherein said protective material includes at least one polymer, said at least one polymer including parylene, parylene derivatives or combinations thereof.

17. The medical device as defined in claim 1, wherein said medical device is a device designed to be positioned in a body passageway, said device including a hypotube, a balloon, a sheath, a guide catheter, an electrophysiology catheter, a guide wire, a stent, a graft, a PFO device, or combinations thereof.

18. The medical device as defined in claim 1, wherein said marker material includes at least one biological agent.

19. The medical device as defined in claim 1, wherein said marker material includes color agent.

20. A method of forming a flexible marker on a medical device including:

a) providing a medical device having an outer surface;

b) applying a layer of an adhesive material to at least a portion of said outer surface of said medical device;

c) applying a layer of metal material to at least a portion of said adhesive material, said metal layer including metal powder, metal salt or combinations thereof, said metal layer visible to at least one form of electromagnetic wave, sound wave, magnetic wave or combinations thereof; and

,

d) applying a protective material over said layer of said adhesive material and said layer of metal material so as to cover at least about 90 percent of said two layers.

21. The method as defined in claim 20, wherein said adhesive material includes a silicone adhesive, a silicone based adhesive, a polyurethane adhesive, a polyurethane based adhesive, an acrylic adhesive, an acrylic based adhesive, or combinations thereof.

22. The method as defined in claim 20, wherein said adhesive layer has an average thickness of about 2-50 microns.

23. The method as defined in claim 20, wherein a majority weight percent of said metal material is a metal powder that includes bismuth powder, molybdenum powder, rhenium powder, tungsten powder, or combinations thereof.

24. The method as defined in claim 20, wherein at least about 95 percent of said metal material has an average particle size of about 5-150 microns.

25. The method as defined in claim 20, wherein a majority of said metal material is radiopaque.

26. The method as defined in claim 20, wherein said protective material has a coating thickness of about 0.1-10 microns.

27. The method as defined in claim 20, wherein said protective material includes at least one polymer, said at least one polymer including parylene, parylene derivatives or combinations thereof.

28. The method as defined in claim 20, wherein said medical device is a device designed to be positioned in a body passageway, said device including a hypotube, a balloon, a sheath, a guide catheter, an electrophysiology catheter, a guide wire, a stent, a graft, a PFO device, or combinations thereof.

29. The method as defined in claim 20, including the step of applying at least one layer of biological agent to said adhesive material, said metal material or combinations thereof prior to applying said layer of protective material.

30. The method as defined in claim 20, including the step of applying at least one layer of biological agent to said layer of protective material.

31. The method as defined in claim 20, including the step of including a color agent in said flexible marker.

32. The method as defined in claim 20, including the use of a mask to at least partially control the location of said adhesive, said metal material, said protective material, or combinations thereof being applied to said medical device.

33. A method of forming a flexible marker on a medical device including:

a) providing a medical device having an outer surface; and

,

b) applying a layer of an adhesive material, a layer of a radiopaque material and a layer of protective material on said outer surface of said medical device.

34. The method as defined in claim 33, including the step of applying said layer of radiopaque material to at least a portion of said adhesive material, said radiopaque material including metal powder, metal salt or combinations thereof.

35. The method as defined in claim 33, including the step of applying said layer of protective material over said layer of said adhesive material, said layer of radiopaque material, or combinations thereof.

36. The method as defined in claim 35, wherein said layer of protective material covering at least about 90 percent of said layer of radiopaque material.

38. The method as defined in claim 33, where in said adhesive layer has an average thickness of about 2-50 microns.

39. The method as defined in claim 33, wherein at least about 95 percent of said radiopaque material has an average particle size of about 5-150 microns.

40. The method as defined in claim 33, wherein said protective material has a coating thickness of about 0.1-10 microns.

41. The method as defined in claim 33, wherein said adhesive material is at least partially applied to said medical device by spraying, air brushing, painting, dip coating, vapor deposition, or combinations thereof.

42. The method as defined in claim 33, wherein said radiopaque material is at least partially applied to said medical device by spraying, air brushing, painting, dip coating or combinations thereof.

43. The method as defined in claim 42, wherein said radiopaque material is applied to said medical device in a substantially even, fluent coating.

44. The method as defined in claim 33, wherein said radiopaque material is at least partially mixed with said adhesive material prior to being applied to said medical device.

45. The method as defined in claim 33, wherein said protective material is at least partially applied to said medical device by spraying, air brushing, painting, dip coating, vapor deposition or combinations thereof.

46. The method as defined in claim 33, including the step of applying at least one layer of biological agent to said adhesive material, said radiopaque material or combinations thereof prior to applying said layer of protective material.

47. The method as defined in claim 33, including the step of applying at least one layer of biological agent to said layer of protective material.

48. The method as defined in claim 33, including the step of including a color agent in said flexible marker.

49. The method as defined in claim 33, including the use of a mask to at least partially control the location of said adhesive, said radiopaque material, said protective material, or combinations thereof being applied to said medical device.