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Miniaturized high-density multichannel electrode array for long-term neuronal recordings

  • US 20060206161A1
  • Filed: 10/18/2005
  • Published: 09/14/2006
  • Est. Priority Date: 03/14/2002
  • Status: Active Grant
First Claim
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1. An intelligent brain pacemaker for a mammal having a cranial nerve not associated with an autonomic function comprising:

  • (a) a multichannel microwire electrode array for acquiring neural signals from a plurality of single neurons comprising;

    (i) a plurality of microwire electrodes;

    (ii) one or more printed circuit boards in electrical connection with the microwire electrodes comprising;

    (1) a plurality of conductive traces spaced apart about 0.015 inches (center to center) or less; and

    (2) a plurality of conductive pads in communication with the conductive traces; and

    (iii) one or more connectors in electrical connection with the conductive pads and having contacts spaced about apart 0.030 inches (center to center) or less;

    (b) a seizure detector adapted to detect seizure-related brain activity of a mammal in real-time, the seizure detector being electrically connected to the multichannel microwire electrode array;

    (c) one or more nerve stimulators adapted to provide electrical stimulation to a mammal'"'"'s cranial nerve not associated with an autonomic function, to terminate or ameliorate the seizure, the one or more nerve simulators being electrically connected to the seizure detector; and

    (d) a power source for providing power to the intelligent brain pacemaker.

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