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System and method for electrochemical detection of biological compounds

  • US 20060207891A1
  • Filed: 04/16/2004
  • Published: 09/21/2006
  • Est. Priority Date: 04/16/2003
  • Status: Active Grant
First Claim
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1. An electrochemical method for detecting a target polynucleotide, comprising:

  • obtaining a first electrochemical signal comprising a portion arising from a first amount of a probe molecule not intercalated with the target polynucleotide;

    modifying an amount of target polynucleotide in fluid communication with the first amount of probe molecule; and

    obtaining a second electrochemical signal comprising a portion arising from a second amount of probe molecule not intercalated with the target polynucleotide.

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