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Compositions and systems for forming crosslinked biomaterials and methods of preparation and use

  • US 20060210602A1
  • Filed: 01/31/2006
  • Published: 09/21/2006
  • Est. Priority Date: 12/18/1995
  • Status: Active Grant
First Claim
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1. A composition for coating a solid implant comprised of:

  • (a) a hydrophilic polymer;

    (b) a crosslinkable component A having m nucleophilic groups, wherein m≧

    2;

    (c) a crosslinkable component B having n electrophilic groups capable of reaction with the m nucleophilic groups to form covalent bonds, wherein n≧

    2 and m+n≧

    4; and

    wherein each of components A and B is biocompatible and crosslinking of the adhesive composition upon contact with moisture results in a biocompatible, crosslinked matrix.

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