Method for preventing and/or treating vaginal and vulval infections
First Claim
1. A method of treatment of a vaginal or vulval infection which comprises administering topically to a subject in need of treatment a therapeutically effective amount of gallic acid or a pharmaceutically acceptable salt thereof.
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Accused Products
Abstract
The invention provides a method for treating and/or preventing a wide scope of vaginal and vulval infections, such as those caused by bacteria, parasites or yeasts, by administering gallic acid to a subject in need of treatment. A composition containing gallic acid for treating vaginal infections is also disclosed. It has been found that gallic acid is capable of selectively inhibiting the growth of Trichomonas vaginalis, a parasite that causes trichomonas vaginitis; Gardnerella vaginalis, a bacterium that causes bacterial vaginosis; and Candida albicans, a yeast that causes candidiasis and vulvitis; while not inhibiting the growth of Lactobacillus acidophilus, the dominant bacteria in a healthy vaginal ecosystem. Gallic acid is safe and cost-effective, and can be used alone or incorporated into different vaginal health products to treat and/or prevent vaginal infections.
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Citations
20 Claims
- 1. A method of treatment of a vaginal or vulval infection which comprises administering topically to a subject in need of treatment a therapeutically effective amount of gallic acid or a pharmaceutically acceptable salt thereof.
- 7. A method of preventing a vaginal or vulval infection which comprises administering topically to a subject in need of treatment a therapeutically effective amount of gallic acid or a pharmaceutically acceptable salt thereof.
- 13. The use of gallic acid or a pharmaceutically acceptable salt thereof in a method of making a medicament for use in a method of preventing or treating a vaginal or vulval infection comprising administering topically a therapeutically effective amount of the gallic acid to a patient in need thereof.
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20. A composition for preventing or treating a vaginal or vulval infection, which comprises a therapeutically effective amount of gallic acid or a pharmaceutically acceptable salt thereof.
Specification