Systems and methods for obtaining, storing, processing and utilizing immunologic information of individuals and populations
First Claim
1. A method for providing selective personalized health care services to one or more individuals in a population of individuals, comprising:
- (a) establishing a record of information representative of the immune status of an individual in the population;
(b) analyzing said record according to one or more defined algorithms; and
(c) generating a recommendation to one or more of said individuals based upon said analysis.
6 Assignments
0 Petitions
Accused Products
Abstract
A system and method for obtaining, storing, processing and utilizing immunologic information of individuals and populations is presented. In exemplary embodiments of the present invention, a biological sample can be taken from one or more individuals and the sample submitted to one or more panels of assays. The results of the assays can be stored and analyzed, and such analysis can include (i) calculating derived quantities which take the results of the assays as inputs, and (ii) submitting the results and the derived quantities to a set of rules, each of which has a defined output state. In exemplary embodiments of the present invention, based upon the output state of the rules, an appropriate recommendation as to one or more immunization or other interventions can be generated and incorporated with provider and patient reminders. In exemplary embodiments of the present invention the results of the assays and the recommendation, as well as additional information specific to the individual can be stored for further analysis. In exemplary embodiments of the present invention the assay panel or panels can be chosen as a function of a defined demographic group or enterprise affinity into which the individual corresponds. In exemplary embodiments a database can be maintained for storing and further processing of all immunologic informatics collected according to the methods of the present invention, and can be further processed or used to optimize the delivery of products and/or services in various commercial, research and governmental contexts.
167 Citations
21 Claims
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1. A method for providing selective personalized health care services to one or more individuals in a population of individuals, comprising:
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(a) establishing a record of information representative of the immune status of an individual in the population;
(b) analyzing said record according to one or more defined algorithms; and
(c) generating a recommendation to one or more of said individuals based upon said analysis. - View Dependent Claims (2, 3, 4, 5)
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6. A method of reducing the incidence of vaccine-preventable disease in a population comprising:
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(a) establishing records of information representative of the immune status of individuals in the population;
(b) updating said records from time to time with current information representative of the immune status of said individuals;
(c) analyzing the information in an individual'"'"'s record according to defined standards for vaccinating individuals; and
(d) vaccinating said individual with one or more vaccines in accordance with said analysis. - View Dependent Claims (7)
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8. A method of reducing the costs associated with treating a vaccine-preventable disease in a population, comprising:
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(a) establishing records of information representative of the immune status of a plurality of individuals in the population;
(b) updating said records from time to time with current information representative of the immune status of said individuals;
(c) analyzing the information in an individual'"'"'s record according to defined standards for vaccinating individuals, and thereby generating a recommendation as to whether or not that individual should be vaccinated.
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9. A method of generating recommendations for vaccinating an individual in a patient population comprising:
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(a) establishing a record of information representative of the immune status of that individual to one or more vaccine-preventable diseases, said record including (1) current information from one or more assays to determine the immunity of said individual to one or more vaccine-preventable diseases, and (2) patient-specific information comprising one or more of said patient'"'"'s medical history, said patient'"'"'s doctors observations, and/or demographic information relating to said patient; and
(b) processing the information so-collected through one or more algorithms created to determine whether or not to vaccinate said individual; and
thereby generating a recommendation for vaccinating or not vaccinating said individual. - View Dependent Claims (10)
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11. A method of optimizing the management of health care for an individual, comprising:
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examining insured'"'"'s immune status;
identifying diseases that the insured is susceptible to and calculating the risk of contraction for each disease;
indentifying prophylactic therapies that could prevent each identified disease;
calculating, for each disease, expected costs of treatment and costs of associated prophylactic therapies;
requiring prophylactic therapies whose cost is less than expected costs of treatment. - View Dependent Claims (12, 13)
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14. A method of creating a database useful for generating health care recommendations for an individual in a population comprising:
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(a) establishing a record of information representative of the immune status of each individual, said record including (1) current information from one or more assays to determine the immunity of said individual to one or more antigens and related complements, and (2) patient-specific information comprising one or more of said patient'"'"'s medical history, said patients doctors observations, and/or demographic information relating to said patient;
(b) recording updated information as recited in (a)(1) and/or (a)(2) from time to time;
(c) providing one or more algorithms to determine recommended health care therapies based upon defined standards; and
(d) modifying said algorithms from time to time based upon data mining of the database.
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15. A method of generating recommendations for vaccinating one or more individuals in a patient population, comprising:
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(a) establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population, to one or more vaccine-preventable diseases, each of said records including (1) current information from one or more assays to determine the immunity of said individual to one or more vaccine-preventable diseases, and (2) patient-specific information comprising one or more of said patients medical history, said patients doctors observations and/or demographic information relating to said patient;
(b) processing the information in said database to find trends or patterns relating to the immune status of individuals in said patient population; and
(c) using the said trends or patterns found in (b) in deciding whether or not to vaccinate an individual.
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16. A method for generating recommendations for vaccinating one or more individuals in a patient population, comprising:
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(a) establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the patient population to one or more vaccine-preventable diseases, each of said records including (1) current information from one or more assays to determine the immunity of said individual to one or more vaccine-preventable diseases, and (2) patient-specific information comprising one or more of said patient'"'"'s medical history, said patients doctors observations and/or demographic information relating to said patient;
(b) providing one or more algorithms to determine whether or not to vaccinate said individuals based upon medical standards;
(c) processing the information in said database to find trends or patterns relating to the immune status of individuals in said patient population and using said trends or patterns to modify said algorithms;
(d) processing the information in a patient'"'"'s record in said algorithms; and
thereby generating a recommendation as to whether or not that individual should be vaccinated.
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17. A method for generating recommendations for vaccinating one or more individuals in a patient population, comprising:
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(a) establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population to one or more vaccine-preventable diseases, each of said records including (i) current information from one or more assays to determine the immunity of said individual to one or more vaccine-preventable diseases; and
(ii) patient-specific information comprising one or more of said patient'"'"'s medical history, said patients doctors observations, and/or demographic information relating to said patient; and
(b) processing the information in said database to find trends or patterns relating to the immune status of individuals in said patient population; and
(c) incorporating information comprising said patterns or trends into one or more algorithms created to determine whether or not to vaccinate an individual within said population.
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18. A method for generating recommendations for vaccinating one or more individuals in a patient population, comprising:
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(a) establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population, to one or more vaccine-preventable diseases, each of said records including (1) current information from one or more assays to determine the immunity of said individual to one or more vaccine-preventable diseases, and (2) patient-specific information comprising one or more of said patients medical history, said patients doctors observations and/or demographic information relating to said patient;
(b) updating said records from time to time with current information as recited in (a)(1) and/or (a)(2);
(c) providing one or more algorithms to determine whether or not to vaccinate said individual based upon medical standards;
(d) processing the information in said database to find trends or patterns relating to the immune status of individuals in said patient population;
(e) modifying the said algorithms to reflect the patterns and trends found in step (d);
(f) processing the information in a patient'"'"'s record through said algorithms, and thereby generating a recommendation for vaccinating or not vaccinating said individual.
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19. A method for generating recommendations for vaccinating one or more individuals in a patient population, comprising:
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(a) establishing a database comprising a plurality of records of information each representative of the immune status of an individual in the population, to one or more vaccine-preventable diseases, each of said records including (i) current information from one or more assays to determine the immunity of said individual to one or more vaccine-preventable diseases, and (ii) patient-specific information comprising one or more of said patient'"'"'s medical history, said patients doctors observations, and/or demographic information relating to said patient;
(b) updating said database from time to time with current information;
(c) providing one or more algorithms to determine whether or not to vaccinate said individuals based upon current medical standards;
(d) processing the information in said database to find trends or patterns relating to the immune status of individuals in said patient population;
(e) incorporating information comprising said patterns or trends into one or more of said algorithms;
(f) processing the information in an individual'"'"'s record through one or more of said algorithms, and thereby generating a recommendation for vaccinating said individual.
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20. A method for assisting a health care provider in reducing the costs associated with treating vaccine-preventable disease in its patient population by selective vaccination of said patients, comprising the steps of:
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(a) establishing records of information representative of the immune status of individuals in the population to one or more vaccine-preventable diseases;
(b) updating said records from time to time with current information representative of the immune status of said individuals;
(c) comparing the information in an individual'"'"'s record with current standards for vaccinating individuals; and
(d) vaccinating said individual if said individual is in need of vaccination with one or more vaccines.
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21. A method of optimizing the management of health care for an individual, comprising:
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examining insured'"'"'s immune status;
identifying diseases that the insured is susceptible to and calculating the risk of contraction for each disease;
indentifying all prophylactic therapies that could prevent each identified disease;
calculating, for all possible combinations of diseases and prophylactic therapies, expected costs of treatment and costs of associated prophylactic therapies;
requiring sets prophylactic therapies optimized for overall cost.
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Specification