Methods for identifying a peptide that binds a geometrical shape
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Abstract
Provided herein are methods, such as phage display assays, for bioengineering peptides that bind to geometrically and/or atomically structured molecular surfaces such as, for example, flat surfaces, smooth curved surfaces, as well as surfaces with periodic, random, or fractal atomic configurations. Surface-binding peptides are provided that are identified using the phage-display methods. Furthermore, scanning probe microscopy (SPM) substrates, biosensors, biochips, and electrodes are provided that include the surface-binding peptides.
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Citations
25 Claims
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1-19. -19. (canceled)
- 20. An isolated peptide or polypeptide comprising at least two peptide units, wherein each peptide unit specifically binds a target geometrical shape, and wherein the isolated peptide or polypeptide is a recombinant peptide or polypeptide.
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25-31. -31. (canceled)
Specification