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Predicting hepatotoxicity using cell based assays

  • US 20060228695A1
  • Filed: 03/13/2006
  • Published: 10/12/2006
  • Est. Priority Date: 07/18/2003
  • Status: Abandoned Application
First Claim
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1. A method of determining whether a stimulus induces a hepatotoxic response or a pathology, the method comprising:

  • (a) receiving one or more images of hepatocytes that have been exposed to a stimulus;

    (b) from the images, automatically generating a plurality features characterizing the hepatocytes; and

    (c) applying the plurality of features to a hepatotoxicity model or a pathology model to thereby classify the stimulus as to hepatotoxicity or pathology.

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